Role of MRI in evaluation of hip joint involvement in juvenile idiopathic arthritis

Elazeem, Mervat I. Abd; Taha, Hanan Ali; El-Sherif, Ashraf Mohamed Hassan

doi:10.1016/j.ejr.2012.03.001

Cited by 9 publications

(15 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This may be explained by the fact that DAS28 does not involve the hip examination in its calculations. 10 Nistala Axial/Coronal postcontrast T1 or T1 FS (if optimal assessment of synovitis/osteitis is required)…”

Section: Mri Versus Clinical Parametermentioning

confidence: 99%

Inflammatory Conditions of the Hip

Schueller-Weidekamm

Teh

2017

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

Most cases of adult hip pain are related to osteoarthritis, so inflammatory causes are often not considered. This review article describes the different entities of hip inflammation and provides an approach on how to differentiate rheumatologic disorders from degenerative changes, synovial tumors, and infection. Indications for imaging, the correct choice of imaging modality, and scanning protocols are also discussed. The differential diagnosis of inflammatory lesions of the hips is addressed in the context of image interpretation.

show abstract

Section: Mri Versus Clinical Parametermentioning

confidence: 99%

Inflammatory Conditions of the Hip

Schueller-Weidekamm

Teh

2017

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

show abstract

“…Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases with an onset before 16 years of age [1,2]. It typically lasts for more than six months, with arthritis present for at least six weeks [1,2] and is the most common form of childhood arthritis [3][4][5][6][7]. Joint involvement usually starts with synovitis and the formation of inflammatory tissue, called the pannus, which destroys hyaline cartilage, erodes the bone and leads to articular destruction and ankylosis [5,6].…”

Section: Introductionmentioning

confidence: 99%

“…Hip arthritis develops in 20-63% of children with JIA, mainly in juveniles with the systemic subtype of the disease [1,4,5,[9][10][11] and is often a predictor of severe disease and high-risk disability [1]. The clinical features are not specific for active hip inflammation and may occur due to previous joint damage [11] or other hip diseases, including malignancies.…”

Section: Introductionmentioning

confidence: 99%

“…The clinical features are not specific for active hip inflammation and may occur due to previous joint damage [11] or other hip diseases, including malignancies. Furthermore, since it is not a superficial joint, hip involvement is particularly difficult to detect clinically, as inflamed synovium and effusions cannot be directly palpated [4,12].…”

Section: Introductionmentioning

confidence: 99%

“…Magnetic resonance imaging (MRI) is a sensitive and valuable technique in pediatric musculoskeletal pathologies and is considered to be the most suitable technique for detecting synovial hypertrophy and bone marrow oedema (BME) [13][14][15][16][17][18]. It allows the visualization of joints in several dimensions using a multiplanar technique [4]. The most common pathologies in JIA are effusions and synovitis, which are most accurately diagnosed using gadolinium injection, following which the highly vascular pannus enhances brightly while joint effusion remains of low signal [19].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

MRI Findings in Hip in Juvenile Idiopathic Arthritis

Ostrowska

Gietka

Mańczak

et al. 2021

JCM

View full text Add to dashboard Cite

The aim of this study was to evaluate if magnetic resonance imaging allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology in juveniles clinically suspected for hip arthritis. This was a retrospective observational study which included 97 children with clinically suspected hip arthritis. Each hip was assessed and scored in MRI for signs of active and destructive inflammatory lesions and developmental lesions. MRI findings between JIA-confirmed patients and without final diagnosis of JIA were compared and the MRI summarized score was calculated, as the sum of scorings of all 24 hip lesions in an individual patient (i.a., effusion, synovitis, bone marrow edema, enthesitis). MRI showed at least one lesion in the majority of patients (95 patients; 98%). Effusion was the most common feature, followed by bone marrow oedema and synovitis. All lesions were more common in patients with a final diagnosis of JIA, especially synovitis and enthesitis (p = 0.037 and p = 0.047). The MRI summarized score was significantly higher in the JIA group than the non-JIA group: 3 (2–5) vs. 2 (2–2), respectively, p = 0.002. Using a cut-off score of 6, the MRI summarized score showed 25% sensitivity and 100% specificity indicating a good ability in discriminating hip arthritis during JIA from non-JIA patients. MRI allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology with good specificity, thus, may be helpful in confirming the diagnosis of JIA.

show abstract

Predictive Value of Magnetic Resonance Imaging in Patients With Juvenile Idiopathic Arthritis in Clinical Remission

Mazzoni

Pistorio

Magnaguagno

et al. 2022

Arthritis Care & Research

View full text Add to dashboard Cite

Objective To define the prevalence of subclinical synovitis on magnetic resonance imaging (MRI) in a large cohort of patients with juvenile idiopathic arthritis (JIA) in clinical remission and to evaluate its predictive value in terms of disease flare and joint deterioration. Methods Ninety patients with clinically inactive JIA who underwent a contrast‐enhanced (CE)–MRI of a previously affected joint were retrospectively included. Each joint was evaluated for synovitis, tenosynovitis, and bone marrow edema. Baseline and follow‐up radiographs were assessed to evaluate structural damage progression. Results CE‐MRI was acquired in 45 wrists, 30 hips, 13 ankles, and 2 knees. Subclinical synovitis was detected in 59 (65.5%) of 90 patients and bone marrow edema in 42 (46.7%) of 90 patients. Fifty‐seven of 90 (63.3%) patients experienced a disease flare during follow‐up. Forty‐four of 59 (74.6%) patients with subclinical synovitis experienced a disease flare versus 13 (41.9%) of 31 patients with no residual synovitis on MRI (P = 0.002). The presence of subclinical synovitis was the best predictor of disease flare on multivariable regression analysis (hazard ratio [HR] 2.45, P = 0.003). Baseline and follow‐up radiographs were available for 54 patients, and 17 (31.5%) of 54 patients experienced radiographic damage progression. The presence of bone marrow edema (HR 4.40, P = 0.045) and being >17 years old (HR 3.51, P = 0.04) were strong predictors of joint damage progression in the multivariable analysis. Conclusion MRI‐detected subclinical inflammation was present in a large proportion of patients with JIA despite clinical remission. Subclinical synovitis and bone marrow edema have been shown to play a role in predicting the risk of disease relapse and joint deterioration, with potential implications for patients' management of the disease.

show abstract

Role of MRI in evaluation of hip joint involvement in juvenile idiopathic arthritis

Cited by 9 publications

References 37 publications

Inflammatory Conditions of the Hip

Inflammatory Conditions of the Hip

MRI Findings in Hip in Juvenile Idiopathic Arthritis

Predictive Value of Magnetic Resonance Imaging in Patients With Juvenile Idiopathic Arthritis in Clinical Remission

Contact Info

Product

Resources

About