2022
DOI: 10.1097/mco.0000000000000822
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Role of muscle-targeted nutritional therapy: new data

Abstract: Purpose of reviewTo provide an updated overview of recent efficacy data on the use of muscle-targeted nutritional therapy, which should consider the optimization of protein and essential amino acids intakes, possibly in combination with supplementation with vitamin D (correction of deficiency/insufficiency status) and v-3 fatty acids. Recent findingsIntervention studies conducted in the last years in different healthcare settings and heterogeneous patient populations support the use of muscle-targeted oral nut… Show more

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Cited by 5 publications
(4 citation statements)
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“…A Spanish study, however, in healthy, physically active and independent elderly did not find a statistically significant association between nutritional status and physical activity but did confirm the association between nutritional status and psychosocial wellbeing [ 53 ]. On the other hand, a reactive and pro-active application of muscle-targeted nutritional therapy appears promising and should be proposed [ 54 ]. However, future research should be directed toward the management of patient populations characterized by substantial muscle wasting, as these have been frequently excluded from previous trials, perhaps to avoid confounding [ 54 ].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…A Spanish study, however, in healthy, physically active and independent elderly did not find a statistically significant association between nutritional status and physical activity but did confirm the association between nutritional status and psychosocial wellbeing [ 53 ]. On the other hand, a reactive and pro-active application of muscle-targeted nutritional therapy appears promising and should be proposed [ 54 ]. However, future research should be directed toward the management of patient populations characterized by substantial muscle wasting, as these have been frequently excluded from previous trials, perhaps to avoid confounding [ 54 ].…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, a reactive and pro-active application of muscle-targeted nutritional therapy appears promising and should be proposed [ 54 ]. However, future research should be directed toward the management of patient populations characterized by substantial muscle wasting, as these have been frequently excluded from previous trials, perhaps to avoid confounding [ 54 ].…”
Section: Discussionmentioning
confidence: 99%
“…On the one hand, patients with vascular or diabetic foot ulcers could take advantage from body weight loss (improved circulation and glucose control), although no evidence is available on the related impact on wound healing. On the other hand, protein balance is crucial to wound healing [2] and nutritional therapy tailored to reduce body weight should be muscle-targeted as well, in order to sustain protein metabolism [7].…”
Section: Basics Of Nutritional Carementioning
confidence: 99%
“…Oral nutritional supplementation enriched with leucine, vitamin D, and omega-3 fatty acids significantly increases inspiratory muscle strength in COPD patients with low muscle mass undergoing high-intensity exercise training [72]. Combined exercise and nutritional interventions show promise as a strategy to increase muscle strength and mass [73,74]. The combination of exercise, such as respiratory muscle training and whole-body resistance training, with nutritional interventions, such as sufficient energy intake and protein fortification, may be applicable to respiratory sarcopenia.…”
Section: Prevention and Treatment Of Respiratory Sarcopeniamentioning
confidence: 99%