Role of Myocardial Strain Analysis by 2-Dimensional Speckle Tracking Echocardiography in Assessment of Severity of Coronary Artery Stenosis in Coronary Artery Disease Patients

Abstract

Background: Myocardial strain analysis by 2D-speckle-tracking echocardiography, which is performed at resting position, offers valuable information about myocardial fiber changes in different types of myocardial diseases. Aim: This study evaluated the role of myocardial strain analysis in assessment of severity of coronary artery stenosis in coronary artery disease patients. Patients and methods: The study was conducted at the Cardiology Department, Benha University Hospitals during the period from January 2023 to July 2023. This study included 100 patients with CAD, patients were divided into two groups: Group A: 50 Patients with Non-ST elevation Acute coronary syndrome. and Group B: 50 Patients with positive or equivocal stress ECG. (Stable coronary artery disease). All patients underwent full history & examination, ECG, conventional & speckle tracking Echocardiography & both Gensini & Syntax scores were calculated for every patient. Results:The study revealed a significant lower GLPSS in Group A compared to Group B (p<0.001). Also as regard the correlation of total longitudinal strain and significant coronary artery disease lesions in each Coronary Artery Territories, a significant higher territorial longitudinal strain correlated with significant lesion in LAD and LCX compared to non-significant lesions in Group A (P value= 0.001) While in Group B a significant higher Territorial longitudinal strain correlated with significant lesion in LAD, LCX and RCA compared to non-significant lesions (P value= 0.001) Conclusion: LVGLS and TLS have an incremental prognostic value and can be used to assess the severity of coronary stenosis in patients with coronary artery disease.