Role of New Drugs for Management of Atrial Fibrillation

Abstract

Use of dronedarone should be limited to patients with paroxysmal or persistent AF and should not be used in patients with heart failure or with permanent AF. Newer antithrombotic agents appear to be promising alternatives for the prevention of stroke in patients with AF; however, more data are needed to understand their role.

Cryoballoon Versus Open Irrigated Radiofrequency Ablation in Patients With Paroxysmal Atrial Fibrillation

“… 3 In addition to their relatively low efficacy, AADs have the disadvantage of causing adverse events, often leading to discontinuation. 4 , 5 Catheter ablation is a well-established technique for treating paroxysmal AF via pulmonary vein (PV) isolation, with a variety of energy sources used, most commonly radiofrequency (RF) or cryoenergy. 6 RF ablation has been shown to be a highly effective first- or second-line treatment for AF; however, it is associated with more immediate and severe complications compared with drug therapy.…”