2018
DOI: 10.1016/j.cca.2018.05.035
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Role of nutritional vitamin D in osteoporosis treatment

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Cited by 44 publications
(32 citation statements)
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References 174 publications
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“…However, researches have shown that osteoblast-lineage cells are not only involved in bone formation, but are also involved in bone resorption supporting the differentiation and activation of osteoclasts [ 47 ]. Imbalance between bone formation and bone resorption may cause some bone related deformities, like osteoporosis [ 48 ].…”
Section: Native Bone Structure and Compositionmentioning
confidence: 99%
“…However, researches have shown that osteoblast-lineage cells are not only involved in bone formation, but are also involved in bone resorption supporting the differentiation and activation of osteoclasts [ 47 ]. Imbalance between bone formation and bone resorption may cause some bone related deformities, like osteoporosis [ 48 ].…”
Section: Native Bone Structure and Compositionmentioning
confidence: 99%
“…Zwiększona aktywność RANKL nad OPG prowadzi do dominacji procesów osteolitycznych. Natomiast przeciwnie zwiększona aktywność OPG prowadzi do osteopetrozy (nadmierne kostnienie), stymuluje kościotworzenie i aktywność osteoblastów [28,29].…”
Section: Wpływ Witaminy D Na Układ Kostnyunclassified
“…Witamina D wywiera bezpośredni efekt na przebudowę kości przez swój receptor (VDR) i jego odmiany polimorficzne [31,32,34,35]. Identyfikacja i rozpoznanie odmian genu VDR powiązanych z niską BMD daje możliwość wczesnego wykrycia ryzyka wystąpienia osteoporozy lub indywidualnej predyspozycji do jej rozwoju [25,29]. Pozwala na wdrożenie profilaktyki zapobiegającej jej występowaniu lub opóźnieniu ujawnienia.…”
Section: Wpływ Polimorfizmów Genu Receptora Witaminy D (Vdr) Na Układunclassified
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“…Listed in the next section is a summary of current nonpharmacologic and nonsurgical treatments for osteoporosis. Nutritional support, such as adequate calcium and vitamin D, as well as exercise are among the crucial cornerstones of the prevention of osteoporosis and are necessary during treatment with pharmacologic agents [1,[11][12][13][14]. However, current evidence has shown that routine calcium and vitamin D supplements in healthy individuals are not needed.…”
Section: Introductionmentioning
confidence: 99%