Role of preoperative multidetector computed tomography diagnosis of solid pseudopapillary tumors of the pancreas with postoperative surgical and histopathological correlation

Paruchuri, Rakhee Kumar; Kuruba, Harvarshdan Ramanjaneylu; Deepthi, P. R.; Prayaga, Aruna K

doi:10.4103/1115-3474.198105

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“…The average size of 6.4 cm in the present study was close to the mean size of 5.8 cm reported by Wang DB et al, [13]. In the series by Paruchuri RK et al, all nine tu mours were encapsulated, and calcification was seen in two out of nine cases, similar to our experience [15].…”

Section: Discussionsupporting

confidence: 91%

“…Haemo rrhagic density may be seen within the lesion. On MDCT the SPN are encapsulated tumours, which are round to oval in shape and exhib it heterogeneous attenuation with peripheral iso-to hyperdense areas [15], similar to our study. Magnetic resonance imaging (M RI) can be diagnostic.…”

Section: Discussionsupporting

confidence: 91%

“…female ratio of 1:10 [2]. seventeen cases in this study were female patients and similar exclusivity in females was reported by Patil TB et al, [12], and other studies have also consistently reported female preponderance [13,14,15]. It is more co mmon in young non-Caucasian wo men, usually Asian and African-American wo men, between the second and third decades of life [16].…”

Section: Discussionsupporting

confidence: 86%

“…CECT scan, ultrasonography (US) and Endosonography (EUS) have been used with variable success in diagnosing SPN. CT scan and EUS are more sensitive and specific and have shown more accuracy in diagnosing SPN [14,15].…”

Section: Discussionmentioning

confidence: 99%

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Solid pseudopapillary neoplasms-experience from a tertiary care centre

et al. 2018

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Introduction: Solid pseudopapillary neoplasms (SPN/FRANTZ TUMOUR) of the pancreas are rare neoplasms of lo w grade malignant potential which were first described in 1959 by Frantz. These account for 0.13-2.7% of pancreatic neoplasms and approximately 13% of surgically resected cystic lesions of the pancreas. We present our experience with these rare tumors. Methods: Total 406 patients with pancreatic tumours were ad mitted in our department during the 10 year period (Between 2007 and 2017) were reviewed, only 18 were diagnosed as having SPN (4.4%). Clinicopathological details, intervention done and follow up of all the cases were studied and reported here. Results: 17 patients were wo man and1was Man with median age of 23 years (range 11 to 54 years). The tumor size ranged from 3.8 to17cm (average 6.4 cm). 12 patients presented with pain in the abdomen, 4 presented with a painless mass, 1 was detected incidentally and1presented with Malena. In 7 patients the tumor was in the pancreatic head, in 3 it was in the neck, and in the remaining 8 it is in the body and tail. CECT was done in all cases. 8 patients underwent Distal pancreatectomy with splenectomy, 1 underwent a PPPD, 6 patients required classical Whipple operation. 3 underwent central pancreatectomy. Immuno histochemistry showed positivity for beta catenin, vimentin, PR receptor and chromogranin negativity. All 18 patients were free of d isease in a median follow-up period of 32 months (range 6-84) months. Conclusion: SPNs are rare neoplasms, typically affecting young women without notable symptoms, with a low malignant potential but excellent prognosis. Radical surgical resection with clear margins is the treatment of choice.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 91%