Role of Probiotics for the Treatment of Peri-Implant Mucositis in Patients With and Without Type 2 Diabetes Mellitus

Alqahtani, Fawaz; Alshaikh, Maha; Mehmood, Abid; Alqhtani, Nasser Raqe; Alkhtani, Fahad; Alenazi, Adel

doi:10.1563/aaid-joi-d-20-00302

Cited by 3 publications

(4 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinical studies have compared the effects of mechanical plaque removal alone or in combination with local application of Limosilactobacillus reuteri in the treatment of peri-implant diseases. The results showed that patients who received probiotic supplementation showed better improvements in clinical parameters such as probing bleeding and probing depth, regardless of the extent of the disease [ 208 , 211 ]. Butera et al suggested that the use of Limosilactobacillus reuteri , Lactobacillus brevis, or Lactiplantibacillus plantarum in the treatment of peri-implant diseases led to varying degrees of improvement in clinical indices such as bleeding on probing, attachment loss, and plaque index [ 212 ].…”

Section: The Role Of Probiotics Against Peri-implant Diseasesmentioning

confidence: 99%

The Potential Value of Probiotics after Dental Implant Placement

Chen

Gan

et al. 2023

Microorganisms

View full text Add to dashboard Cite

Dental implantation is currently the optimal solution for tooth loss. However, the health and stability of dental implants have emerged as global public health concerns. Dental implant placement, healing of the surgical site, osseointegration, stability of bone tissues, and prevention of peri-implant diseases are challenges faced in achieving the long-term health and stability of implants. These have been ongoing concerns in the field of oral implantation. Probiotics, as beneficial microorganisms, play a significant role in the body by inhibiting pathogens, promoting bone tissue homeostasis, and facilitating tissue regeneration, modulating immune-inflammatory levels. This review explores the potential of probiotics in addressing post-implantation challenges. We summarize the existing research regarding the importance of probiotics in managing dental implant health and advocate for further research into their potential applications.

show abstract

Section: The Role Of Probiotics Against Peri-implant Diseasesmentioning

confidence: 99%

The Potential Value of Probiotics after Dental Implant Placement

Chen

Gan

et al. 2023

Microorganisms

View full text Add to dashboard Cite

show abstract

“…Of the RCTs, five studies [8,10,11,19,21] included periodontally healthy patients, one study [18] included edentulous patients, two studies [9,23] did not report any previous periodontal diagnostic information, and one study [22] included patients with a history of chronic periodontitis.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…They have been extensively studied for their potential to improve intestinal health and stimulate the immune system [6]. However, there is a growing body of evidence [7][8][9][10] suggesting that probiotics may also be beneficial in the treatment of peri-implant mucositis. Probiotics containing Lactobacillus spp.…”

Section: Introductionmentioning

confidence: 99%

Effect of Adjunctive Use of Probiotics in the Treatment of Peri-Implant Mucositis: A Systematic Review and Meta-Analysis

Villafuerte,

Martinez,

Santos

2023

Applied Sciences

View full text Add to dashboard Cite

This review was performed to analyze evidence from the scientific literature of the adjunctive effect of probiotics in the treatment of peri-implant mucositis (PiM). Only randomized clinical trials evaluating the effect of probiotics as an adjunct to mechanical debridement in PiM were included. A search was performed in PubMed/MEDLINE, LILACS, ScienceDirect, and Web of Science to identify articles published in English up to January 2023. The quality of the studies was evaluated using the JADAD scale, and the risk of bias was assessed with the Cochrane Collaboration assessment tool. Of the 159 potentially relevant studies, only 9 studies were included. The most commonly used strain was Lactobacillus reuteri, and the meta-analysis was conducted on studies with a follow-up period of 3 to 6 months, observing an overall effect on the reduction of bleeding on probing (BOP) at 3 and 6 months (WMD = −1.13, 95% CI = −1.95 to −0.30, p = 0.007; and WMD = −1.32, 95% CI = −2.15 to −0.48, p = 0.002), plaque index (PI) at 3 months (WMD = −1.22, 95% CI = −2.25 to −0.19, p = 0.02), and probing pocket depth (PPD) at 3 and 6 months, which was statistically significant in favor of the probiotic group (WMD = −1.34, 95% CI = −2.42 to −0.25, p = 0.02 and WMD = −1.36, 95% CI = −2.61 to −0.11, p = 0.03). On the other hand, there were no significant changes in the subgingival microflora around the implants with the use of probiotics. Probiotic therapy, as an adjunct to mechanical debridement, promotes a greater reduction in BOP, PPD, and PI, in relation to the control group without probiotics.

show abstract

“…Mucositis is a prevalent and harmful illness. Its prevalence during standard chemotherapy is between 20 and 40%, and it may reach 80% in individuals undergoing high-dose chemotherapy (such as a conditioning regimen for hematopoietic stem cell transplantation or HSCT) [9]. Approximately 60% of patients who experience it use mammalian targets of rapamycin Pharmaceuticals 2023, 16, 654 2 of 13 inhibitors such as everolimus and temsirolimus.…”

Section: Introductionmentioning

confidence: 99%

Probiotics in the Treatment of Radiotherapy-Induced Oral Mucositis: Systematic Review with Meta-Analysis

et al. 2023

View full text Add to dashboard Cite

The inflammatory injury of the mucous membranes lining the digestive tract, from the mouth to the anus, is called mucositis. One of the intriguing and compelling new therapeutic modalities that has emerged in recent decades due to advances in our understanding of this condition’s pathophysiology is probiotics. The purpose of this meta-analysis is to evaluate the efficiency of probiotics in the treatment of chemotherapy-induced mucositis for head and neck malignancies; a literature search was performed on PubMed, Lilacs, and Web of Science, and articles published from 2000 to 31 January 2023 were considered, according to the keywords entered. The term “Probiotics” was combined with “oral mucositis” using the Boolean connector AND; at the end of the research, 189 studies were identified from the search on the three engines. Only three were used to draw up the present systematic study and metanalysis; this meta-analysis showed that the treatment of mucositis with probiotics is an effective method, and the analysis of the results of these studies showed that the use of probiotics promoted a decrease in the severity of mucositis symptoms.

show abstract

Role of Probiotics for the Treatment of Peri-Implant Mucositis in Patients With and Without Type 2 Diabetes Mellitus

Cited by 3 publications

References 38 publications

The Potential Value of Probiotics after Dental Implant Placement

The Potential Value of Probiotics after Dental Implant Placement

Effect of Adjunctive Use of Probiotics in the Treatment of Peri-Implant Mucositis: A Systematic Review and Meta-Analysis

Probiotics in the Treatment of Radiotherapy-Induced Oral Mucositis: Systematic Review with Meta-Analysis

Contact Info

Product

Resources

About