Role of Probiotics in Human Health

Abstract

Certain bacteria, known as probiotics, have had a vastly beneficial effect on people's health; considering their benefits they have been mixed with a wide variety of foods for several decades now. The ability of probiotics to modify the immunological response of the host, antagonize pathogenic microbes, or compete for adhesion sites with pathogenic microorganisms is related to the action of probiotics against microorganisms. Infections of the digestive tract, irritable bowel, lactose intolerance, allergies, infections of the urogenital tract, cystic fibrosis, and various cancers can all be prevented and treated with the use of probiotics. They can reduce the side effects of various antibodies. In the field of oral health, dental caries, periodontal disease, and bad breath can be prevented and treated with the use of probiotics. The findings of several of these clinical studies indicate that probiotics may be beneficial in the treatment and prevention of various diseases and health issues. Validation of a significant number of these clinical investigations is necessary before the results can be applied to the clinical setting. Clinical studies play an important part in such investigations, and in the not-too-distant future, the outcomes of such trials will determine whether or not probiotics are effective in the treatment of disease. This article will attempt to provide a summary of the available literature on the benefits that these probiotics have with regard to health and disease.Probiotics are foods and/or supplements that contain non-pathogenic microbes such as bacteria and yeast that colonize the gut and can potentially yield a variety of health benefits. Research into the various ways in which probiotic bacteria could be used in the treatment of intestinal disorders is ongoing. Thanks to clinical studies and laboratory experiments, we now know more about how probiotics affect gut microbiome disorders. Studies can prove that probiotics can alleviate a variety of gastrointestinal ailments and improve overall health. This article concentrates on probiotics and commensal microbes, as well as their potential role in gut microbiome-related illnesses. In this section, we mark certain areas that need further work and studies so as to enhance our understanding of how probiotics help in the treatment and reduction of chances of gastrointestinal diseases.

Probiotics: Health benefits, food application, and colonization in the human gastrointestinal tract

“…Irritable bowel syndrome (IBS), celiac disease, and other intestinal illnesses have been linked to a deficiency of beneficial bacteria in the gut. Beneficial probiotics in the gastrointestinal tract inhibit pathogenic microbes by competing for space and resources, thereby preventing them from infiltrating and proliferating (Bodke & Jogdand, 2022). Probiotics can beneficially modulate the human immune system in conjunction with the host's original microbiota (Bodke & Jogdand, 2022).…”

“…Beneficial probiotics in the gastrointestinal tract inhibit pathogenic microbes by competing for space and resources, thereby preventing them from infiltrating and proliferating (Bodke & Jogdand, 2022). Probiotics can beneficially modulate the human immune system in conjunction with the host's original microbiota (Bodke & Jogdand, 2022). Upon ingesting probiotics, they first adhere to the recognition receptors on the surface of the intestinal epithelial cells, thus triggering a cascade of immunological responses (Raheem et al, 2021).…”

Probiotics and postbiotics play a role in maintaining dermal health

“…10 They may be used to treat inflammatory diseases, urogenital infections, and a variety of gastrointestinal illnesses. 11 They have positive immunomodulatory effects, including intraepithelial modulation and activation, as well as cytokine synthesis triggered by macrophage and natural killer cell activation. 12,13 Due to the fact that probiotic bacteria perform several activities, they are currently being employed in a wide variety of scientific fields to combat a variety of ailments.…”

Probiotic-Fermented Camel Milk Attenuates Neurodegenerative Symptoms via SOX5/miR-218 Axis Orchestration in Mouse Models

“…Recently, extensive studies have been conducted on the effect of fermented food products on human health, including probiotics (PBT) and fermented dairy products, as either prophylactic or therapeutic nutraceuticals [ 1 ]. PBTs are considered one of the food supplements that are produced using non-pathogenic microorganisms that improve and restore gut commensal microbiomes (GMs) [ 2 ]. Reports evidenced that PBTs could potentially improve a variety of gastrointestinal disorders and improve health [ 3 ].…”

“…Several studies have shown the ameliorative properties of PBTs as food supplements via the regulation of imbalanced GM [ 7 ]. Moreover, PBTs have demonstrated alleviation of immuno-inflammatory issues associated with multiple health conditions, including diabetes, inflammatory bowel syndrome (IBS), neuro-inflammatory illnesses and MS [ 2 , 8 , 9 , 10 ]. Currently, live PBT cultures are part of fermented dairy products.…”