Role of Probiotics on Oral Health - A Randomized, Double Blind, Placebo-Controlled Microbiological Study

Dhawan, Sanjay; Dhawan, Rajan

doi:10.5171/2013.736993

Cited by 4 publications

(4 citation statements)

References 24 publications

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“…Few studies had been carried out to deliver oral probiotics using capsules (Table 2). Dhawan and Dhawan [5] there is a significant reduction in plaque and gingivitis score from week 1 to week 3 in the probiotic group. However, after going through the study, it is found that the researchers did not compare statistically on the plaque, gingivitis and S. mutans level between the treatment weeks within the probiotic group.…”

Section: Capsulesmentioning

confidence: 87%

“…Few studies had been carried out to deliver oral probiotics using capsules (). Dhawan and Dhawan [5] evaluated the effectiveness of probiotics capsules ( Lactobacillus sporogenes , Streptococcus faecalis T-110JPC, Clostridium butyrium TO-A, Bacillus mesentricus TO-AJPC) on the plaque, gingivitis and S. mutans level in chronic gingivitis patients where the patients were divided into two groups (placebo and probiotic group).…”

Section: Oral Probiotic With Different Delivery Carriersmentioning

confidence: 99%

“…For a century, probiotic has been widely studied and reported to be able to exert beneficial health effects by treating or preventing several medical conditions such as diarrhoea, inflammatory bowel diseases, colon cancer, and cholesterol-lowering [1]. In recent years, oral probiotics have shown their potential in preventing and treating oral diseases [3][4][5][6]. However, limited studies have been conducted to show the effectiveness of probiotics in improving oral health.…”

Section: Introductionmentioning

confidence: 99%

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Oral probiotic and its delivery carriers to improve oral health: A review

How

Yeo

2021

Microbiology

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In recent years, oral probiotics have been researched on their effectiveness in reducing and preventing oral diseases. Oral probiotics could be introduced into the oral cavity to keep the equilibrium of the microbiome. Hence, the delivery carrier for oral probiotics plays an important factor to ensure a high number of oral probiotics were delivered and released into the oral cavity. This review presents a brief overview of oral microbiota and the role of oral probiotics in reducing oral diseases. Moreover, important aspects of the oral probiotic product such as viability, adherence ability, health effects, safety, and delivery site were discussed. Besides that, the importance of utilizing indigenous oral probiotics was also emphasized. Oral probiotics are commonly found in the market in the form of chewing tablets, lozenges, and capsules. Hence, the oral probiotic carriers currently used in the market and research were reviewed. Furthermore, this review introduces new potential oral probiotic delivery carriers such as oral strip, bucco-adhesive gel, and mouthwash. Their effectiveness in delivering oral probiotics for oral health was also explored.

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Section: Capsulesmentioning

confidence: 87%

Section: Oral Probiotic With Different Delivery Carriersmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Oral probiotic and its delivery carriers to improve oral health: A review

How

Yeo

2021

Microbiology

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“…Recent research, including clinical trials, clearly suggests that probiotics can help prevent and treat oral infections, such as tooth decay and other periodontal diseases. Probiotics have the unique capacity to form a biofilm, which functions as a protective lining and aids in the replacement of any pathogen that thrives in biofilms [ 15 , 16 ].…”

Section: Discussionmentioning

confidence: 99%

An In Vitro Evaluation of the Antimicrobial Activity of Probiotics Against Endodontic Pathogens

Teja¹,

Raju²,

Reddy³

et al. 2022

Cureus

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Background and aim: Despite scientific evidence that even some microorganisms may be useful, endodontic intervention has persisted to prioritize the removal of all microorganisms from the root canal system. Indeed, information regarding the significant role of probiotic microorganisms in endodontic treatment has been sparse. This study aimed to carry out an in vitro evaluation of the antimicrobial activity of probiotics against endodontic pathogens. Methods: The evaluation was carried out in three stages. In Stage 1, the agar cup well procedure was used to analyse the efficiency of probiotics microorganisms against Enterococcus faecalis bacteria and Candida albicans microorganisms in the planktonic stage. In Stage 2, a deferred antagonistic experiment was used to determine the activity of probiotic microorganisms against endodontic pathogens like E. faecalis and C. albicans in the planktonic phase. In Stage 3, biofilm phase evaluation of an intracanal probiotic microorganism carrier was done. The region of maximum inhibition was measured at the end of Stages 1 and 2. The antimicrobial activity was recognized when the dimension of the region of maximum inhibition was 10 mm or above. The colony-forming unit/millilitre was measured at the end of Stage 3.Results: There was marked antimicrobial activity of probiotic microorganisms against the pathogenic microorganisms E. faecalis as well as C. albicans in Stages 1 and 3, i.e., during the evaluation involving agar cup and evaluation at the biofilm stage. However, no antimicrobial activity of probiotic microorganisms was observed against pathogenic endodontic microorganisms in Stage 2, i.e., during evaluation involving the use of the deferred antagonistic technique.Conclusion: It can be concluded that probiotic therapy is a promising antibacterial treatment approach that should be further investigated. This study shows that probiotics can help effectively in endodontic treatment and that more in vitro as well as in vivo research is needed to fully appreciate the advantages of bacteriotherapy in the field of endodontics.

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