Role of Rho-associated kinases and their inhibitor fasudil in neurodegenerative diseases
Qiuyan Ye,
Xue Li,
Wei Gao
et al.
Abstract:Neurodegenerative diseases (NDDs) are prevalent in the elderly. The pathogenesis of NDDs is complex, and currently, there is no cure available. With the increase in aging population, over 20 million people are affected by common NDDs alone (Alzheimer’s disease and Parkinson’s disease). Therefore, NDDs have profound negative impacts on patients, their families, and society, making them a major global health concern. Rho-associated kinases (ROCKs) belong to the serine/threonine protein kinases family, which modu… Show more
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