This paper discusses the analysis of subject matter structure for purposes of designing instruction. The underlying assumption is that subject matter structures provide an important basis for deciding how to sequence and synthesize the "modules" of a subject matter area. Four types of fundamental structures are briefly describe~and illustrated: the learning hierarchy, the procedural hierarchy, the taxonomy, and the model. Then a theoretical framework is presented for classifying types of subject matter content -both "modules" and structures. Finally, some implications of these content classifications are discussed. The classification of "modules" is hypothesized to be valuable for prescribing strategies for the presentation of single "modules", and the classification of structures is hypothesized to be valuable for prescribing strategies for selecting, sequencing, synthesizing, and summarizing related "modules". The need to take into account more than one kind of structure in the process of instructional design is emphasized.Subject matter structure refers to the interrelationships among the components [ 1 ] of a subject matter. The structure of subject matter Can be, and has been, analyzed for a variety of purposes. This paper discusses the analysis of subject matter structure for the purpose of designing instruction -textbooks, courses, workbooks, etc. The underlying motivation for this analysis is our belief that subject matter structures have important implications for the best ways to sequence (i.e., order) and to synthesize (i.e., show the interrelationships among) related components of a subject matter.Our work in instructional strategies has led us to the conclusion that "structural" strategies such as synthesizers (i.e., explicit descriptions of types of pervasive relations among subject matter components) can have a far greater impact on instructional outcomes than the vast majority of instructional strategy variables that have been investigated to date. The purpose of this paper is to identify and describe some of those aspects of subject matter structure which may have the most prescriptive power for the development of, and the selection of, optimal structural strategies (e.g., the selection, sequencing, synthesizing, and summarizing of related components of a subject matter).