Role of scrape cytology in the intraoperative diagnosis of tumor

Kolte, Sachin; Satarkar, Rahul N

doi:10.4103/0970-9371.71871

Cited by 22 publications

(22 citation statements)

References 12 publications

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“…The time elapsed for giving an intraoperative diagnosis is another area of concern with FS. Average turnaround time is around 20 min in a study [12] involving around 700 laboratories versus 10 min for IOC by Kolte and Satarkar [13], measured from the time the pathologists received the specimens to the time that the pathologists informed the operating surgeon on the diagnosis, and 5 min in our study.…”

Section: Discussionmentioning

confidence: 97%

Role of Field Staining in the Cytological Assessment of Intraoperative Surgical Specimens

Ojha¹,

Jain²,

Meenai³

et al. 2018

Acta Cytologica

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Objective: To study the role of Field staining in scrape smears for intraoperative cytological (IOC) diagnosis. Specimens were assessed for categorizing among benign and malignant lesions, lymph node status, and adequacy of surgical cut margins as per specimen. Technique, adequacy, and quality were assessed along with comparison of cytological diagnosis with final histopathological diagnosis obtained on routine hematoxylin and eosin-stained slides. Study Design: A prospective observational study was conducted over a period of 1 year from November 2016 to October 2017 in the Department of Pathology of our Institute. Results: 50 cases were studied, and scrape smears were stained with Field stain. Results were satisfactory in terms of adequacy and attaining the objectives of the study. A diagnostic accuracy of 98% was observed with an average turnaround time of 5 min. A single case of low-grade glioma was found to be discordant. Conclusions: Use of Field staining for intraoperative cytological assessment of surgical specimens has 98% concordance with the final histopathological diagnosis and achieved the aim of the study. With its low costs, easy availability, short turnaround time, and simple technique, it will be helpful in IOC as an alternative to present techniques especially in financially constrained settings.

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Section: Discussionmentioning

confidence: 97%

Role of Field Staining in the Cytological Assessment of Intraoperative Surgical Specimens

Ojha¹,

Jain²,

Meenai³

et al. 2018

Acta Cytologica

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“…Hence, scrape cytology can be employed routinely in the intraoperative diagnosis of tumors. The use of either frozen section or intraoperative scrape cytological examination alone has an acceptable rate (93-97%) of correct diagnosis with regard to interpretation of benign versus malignant 8 .…”

Section: Didarul Alammentioning

confidence: 99%

“…Commonly used methods for obtaining and preparing cells for intraoperative cytological evaluation are imprint cytology, Fine Needle Aspiration Cytology (FNAC) and scrape smear preparation. [8] Scrape cytology is a modification of imprint cytology and its diagnostic accuracy is better than imprint cytology. Scraping of the cut surface prior to smearing facilitates the harvesting of cells.…”

Section: Didarul Alammentioning

confidence: 99%

Role of Intraoperative Scrape Cytology in Diagnosis of Palpable Breast Lump

Mosarrat

Rahman

Ahamad

et al. 2019

Chatt Maa Shi Hosp Med Coll J

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Background: Diseases of the breast constitute a significant proportion of surgical cases and frequently, the need arises to distinguish benign from malignant lesions prior to definitive treatment. So far, Frozen Section (FS) is the standard technique with high level of validity. However, intraoperative scrape cytology can be adopted when special facilities of FS are not available. Methods: This study designed with the aim to evaluate the value of Intraoperative Scrape Cytology (IOSC) in providing rapid and accurate diagnosis for breast lump and to compare its diagnostic yield with that of paraffin sections. This cross sectional descriptive study was carried out in the Department of Pathology, Chittagong Medical College in collaboration with Department of Surgery of this institution from October 2013 to September 2014. The study conducted on 123 patients with breast lumps who underwent operative treatment. Scrapings were taken from each specimen before formalin fixation and stained by rapid Papanicolaou staining. In each case their accuracy was compared to histopathological diagnosis. Statistical analysis done employing c2 test. Results: Out of 123 cases studied, 122 could be correctly differentiated into benign and malignant tumors with an accuracy rate of 99.19%. Conclusion: Intraoperative Scrape Cytology (IOSC) is a simple, accurate, rapid and cost-effective diagnostic tool, not requiring specific instruments in contrast to frozen section, can be used peroperatively for both diagnosis and management of breast lump. Chatt Maa Shi Hosp Med Coll J; Vol.17 (2); Jul 2018; Page 26-30

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“…The method is simple, rapid, inexpensive and does not require special techniques or instruments [4,5]. It does not alter the utility of the specimen for subsequent histopathological examination [6]. The limitation of imprint cytology is its inability to distinguish in-situ from infiltrating carcinomas and to evaluate the depth the invasion.…”

Section: Introductionmentioning

confidence: 99%

Role of imprint cytology and frozen section in the diagnosis of tumours

H.V.

et al. 2018

Trop J Pathol Microbiol

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Introduction: Imprint cytology is an economical, simple and quick method with excellent cytological clarity but cannot provide information on the depth of invasion. Frozen section is the standard method of intraoperative diagnosis but is limited by its cost, need of qualified technical staff and the freezing arte facts. Thus, both the techniques have their own limitations and combining these techniques helps in achieving high diagnostic accuracy rates. Aims: 1. To assess the combined role of imprint cytology and frozen section in the diagnosis of tumours of various organs. 2. To compare the diagnostic accuracy of imprint cytology and frozen section individually with that of the histopathological diagnosis. Materials and Methods: The present study was done in the pathology department of Bangalore medical college and research institute for a period of one year. A total of 50 surgical specimens from various organs were studied using imprint cytology and frozen section. The results of both the techniques were compared with the gold standard histopathological diagnosis. Results: Out of 50 cases, majority were ovarian neoplasms comprising of 21 (42%) cases followed by thyroid (14%), breast (12%) and salivary gland (10%) neoplasms. The majority of the cases were malignant (50%) followed by beingn (40%), borderline (6%) and metastatic (4%). The overall diagnostic accuracy of imprint cytology and frozen section in various organs were 94% and 98%respectively. The combined diagnostic accuracy was 98%. Conclusion: Imprint cytology and frozen sections are interdependable intraoperative diagnostic modalities. Imprint cytology alone may not be able to provide a correct diagnosis. Thus, a combination of imprint cytology and frozen section helps in achieving high diagnostic accuracy rates and in distinguishing benign and malignant lesions.

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Role of scrape cytology in the intraoperative diagnosis of tumor

Cited by 22 publications

References 12 publications

Role of Field Staining in the Cytological Assessment of Intraoperative Surgical Specimens

Role of Field Staining in the Cytological Assessment of Intraoperative Surgical Specimens

Role of Intraoperative Scrape Cytology in Diagnosis of Palpable Breast Lump

Role of imprint cytology and frozen section in the diagnosis of tumours

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