Role of semen analysis in subfertile couples

Steeg, Jan Willem van der; Steures, Pieternel; Eijkemans, Marinus J.C.; Habbema, J. Dik F.; Hompes, Peter G.A.; Kremer, J.A.M.; Leeuw-Harmsen, Loes van der; Bossuyt, Patrick M.; Repping, Sjoerd; Silber, Sherman J.; Mol, Ben Willem J.; Veen, Fulco van der

doi:10.1016/j.fertnstert.2010.02.024

Cited by 133 publications

(67 citation statements)

References 29 publications

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“…However, semen characteristics that discriminate between infertile and fertile men are not well defined, and results fall within the accepted reference ranges in up to 40% of those suffering from infertility (12)(13)(14). Not only sperm production varies widely in same men but also conventional semen analysis neither tests for the diverse array of biological properties spermatozoa express as an eminently specialized cell nor accounts for putative sperm dysfunctions such as immature chromatin or fragmented DNA.…”

Section: Importance and Limitations Of Semen Analysis For Male Infertmentioning

confidence: 97%

Clinical relevance of routine semen analysis and controversies surrounding the 2010 World Health Organization criteria for semen examination

2014

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Section: Importance and Limitations Of Semen Analysis For Male Infertmentioning

confidence: 97%

Clinical relevance of routine semen analysis and controversies surrounding the 2010 World Health Organization criteria for semen examination

2014

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“…However, a male infertility factor may be present even when the semen analysis is normal. The results of SA within normal ranges, as conventionally assessed for sperm count, motility, and morphology, have low predictive power of only 60 % to forecast the occurrence of a natural pregnancy [3].…”

Section: Definitionsmentioning

confidence: 98%

Engaging Practicing Gynecologists in the Management of Infertile Men

Agarwal

Hamada

Esteves³

2014

J Obstet Gynecol India

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In the modern era, contemporary management of male infertility has undergone groundbreaking changes with the introduction of new concepts, advanced testing, and therapeutic interventions. As practicing gynecologists are often the first physicians who encounter an infertile couple, it is essential that these clinicians are continuously updated about the new pearls and pitfalls of male infertility management. Semen analysis is commonly ordered by gynecologists. In 2010, the WHO released new cutoff reference values for the semen parameters adopting novel methodology, which has incited much debate. Reference values have been lowered in comparison with previous standards, with a direct clinical implication in decision-making strategies. Specialized sperm-function tests, such as sperm oxidative stress and sperm chromatin integrity assessments, became clinically available, thus offering an opportunity to better understand sperm dysfunctions concealed during routine semen analysis. Furthermore, the initial counseling of azoospermic men by an andrologically well educated gynecologist may alleviate the misconception and distress surrounding the false belief of sterility, and will clarify the 123 available options of percutaneous and microsurgical spermretrieval techniques and assisted conception outcome. Regarding varicocele, which is commonly seen in infertile males, it is now clear that the best treatment option for infertile men with clinical varicocele is the microsurgical vein ligation. Natural conception is significantly improved after varicocelectomy, and recent data suggest that such treatment optimizes reproductive outcome of couples undergoing ICSI or micro-TESE sperm retrieval. Lastly, new therapeutic interventions, including oral antioxidant therapy and lifestyle modifications, have gained increasing attention, as they aid in alleviating male infertility.

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“…Manche Autoren fordern sogar eine routinemäßige Bestimmung der ovariellen Funktionsreserve vor Beginn der Verhütung [28]. Die Fertilität eines Paars und das reproduktive Potenzial werden natürlich auch durch die Qualität des Ejakulats beeinflusst [29,30]. Im Vordergrund stehen die Spermienkonzentration und Progressivmotilität.…”

Section: » Vor Allem Bei Subfertilenunclassified

Natürliche Fertilität und Kinderwunsch

Gnoth

Mallmann

2016

Gynäkologische Endokrinologie

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Role of semen analysis in subfertile couples

Cited by 133 publications

References 29 publications

Clinical relevance of routine semen analysis and controversies surrounding the 2010 World Health Organization criteria for semen examination

Clinical relevance of routine semen analysis and controversies surrounding the 2010 World Health Organization criteria for semen examination

Engaging Practicing Gynecologists in the Management of Infertile Men

Natürliche Fertilität und Kinderwunsch

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