Role of serum albumin level compared to CD4 cell count as a marker of immunosuppression in HIV/AIDS patients

Abstract

Introduction:-HIV infection is very widespread affecting the human society but due to financial constraints there is a need to identify an alternate prognostic markers of immunosuppression other than CD4+ cell count in HIV. Aims:-To evaluate the role of serum albumin level compared to CD4+ cell count as a markers of immunosuppression in HIV/AIDS patients. Material and Methods:-This prospective follow up case control study included 60 HIV/AIDS patients and controls were age and sex matched normal people. Results:-In our study the mean albumin level was 2.70 ± 0.6, There was a Significant positive correlation between CD4 count and albumin level. p=.037, P<0.001. This suggest that the serum albumin marker could be used as a surrogate marker for immunosuppression in HIV/AIDS patients. Conclusion:-Albumin could be used as a supplementary marker for immunosuppression in HIV/AIDS patients.