Role of serum sodium on heart, anemia, and diabetes patients

Abstract

This article examines the role of serum sodium (SNa) on heart, anemia, and diabetes patients based on a real data set of 299 patients and probabilistic modeling. It is derived herein that mean SNa is positively associated with the marginal effects of platelets count (PLC) (P = 0.0019), anemia status (ANS) (P = 0.1053) (partially), creatinine phosphokinase (CRP) (P = 0.0462), smoking habit (SMH) (P= 0.1017), SEX (P = 0.0029), and the joint interaction effects (JIEs) of ejection fraction (EJF) and the status of high blood pressure (HBP), i.e., EJF*HBP (P = 0.1398); ANS and death event (DEE), i.e., ANS*DEE (P = 0.0009); age and time to follow-up (TTF), i.e., AGE*TTF (P = 0.0700); age and serum creatinine (SEC), i.e., AGE*SEC (P = 0.0901); EJF and SEC, i.e., EJF*SEC (P = 0.0044); and CRP and TTF, i.e., CRP*TTF (P = 0.0021). Mean SNa is negatively associated with the marginal effects of DEE (P = 0.0001), TTF (P= 0.0521), SEC (P = 0.0028), diabetes status (DIS) (P = 0.0121), and the JIEs of PLC*ANS (P = 0.1064), CRP*SMH (P = 0.0274), CRP*HBP (P = 0.0044), AGE*PLC (P = 0.0811), AGE*SEX (P = 0.0008), AGE*CRP (P = 0.0463), and EJF*PLC (P = 0.0420). The variance of SNa is marginally positively associated with AGE (P = 0.0933), DEE (P = 0.1408), and the JIEs of AGE*ANS (P = 0.0575), EJF*SEX (P = 0.1001), SEC*SMH (P = 0.0091), EJF*TTF (P = 0.0008), CRP*DIS (P = 0.0039), EJF*DEE (P = 0.0022), and SEC*DIS (P = 0.0001). Also the variance of SNa is marginally negatively associated with ANS (P = 0.0631), EJF (P = 0.0008), DIS (P = 0.0548), PLC (P = 0.0023), SMH (P = 0.0242), TTF (P = 0.0018), CRP (P = 0.0027), and the JIEs of AGE*DEE (P = 0.0003) and SEC*SEX (P = 0.1327). SNa maintains a complex relationship with different patients and factors, and they have both marginal and JIEs on SNa. Medical practitioners and researchers should care about the complicated functional roles of SNa.

Impacts of Serum Creatinine Phosphokinase on Heart, Diabetes and Anaemia Patients

“…The study characters such as attributes and variables in the current research are separately illustrated in the article by Chicco and Jurman [24]. Recently an article by Das et al [25] has shortly described the data set. For more information on the data set, interested authors are requested to go through the articles [21,22,24,25].…”

“…Recently an article by Das et al [25] has shortly described the data set. For more information on the data set, interested authors are requested to go through the articles [21,22,24,25].…”