Role of single serum progesterone assay in threatened abortion as a predictor of viable pregnancy

Abstract

Background: Low progesterone levels have been linked to increased risk of miscarriage in first trimester of pregnancy. Methods: The observational, cross-sectional study was conducted over 100 pregnant females in first trimester of pregnancy < 12 weeks. All patients were subjected to sonography to confirm pregnancy & serum progesterone level testing immediately after admission and before initiation of treatment. Result: After analysis of the results, cut off value of serum progesterone as determined in this study came out to be 9.9 ng/ml with 94.9% sensitivity & 92.7% specificity. Conclusion: The value of serum progesterone estimation was of great help in differentiating between viable and non-viable pregnancy.