Role of sunshine vitamin &amp;#147;D&amp;#148; sufficiency in male and female infertility

Kumari, Kalpana; Hadalagi, Dr. Nandini Malleshappa

doi:10.5455/2320-1770.ijrcog20150404

Cited by 7 publications

(4 citation statements)

References 16 publications

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“…Raja Kumari et al, [18] study that studied the role of sunshine vitamin "D" sufficiency in male and female infertility partially in line with our study and found that women with sufficient levels of vitamin D show higher implantation rates, higher rates of clinical pregnancy in IVF and ET cycles. Its most important role in reproduction may be at the endometrial level.…”

Section: Discussionsupporting

confidence: 90%

Association Between Vitamin D Deficiency and Unexplained Infertility

Ramy,

Rafaat,

Abdel Hameed

et al. 2023

Evidence Based Women's Health Journal

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Background:The causes of female infertility are different and include genetic and anatomic abnormalities as well as endocrine and autoimmune disorders (ADs). Vitamin D might influence steroidogenesis of both estradiol and progesterone in healthy women where low levels of 25(OH)D levels might be associated with infertility. Aim of the Work:To elucidate if there is relationship between vitamin D and unexplained infertility and if it more prevalent in them. Patients and Methods: This case-control study was conducted at Ain Shams University Maternity Hospital during the period between October 2018-april 2019. A total of 70 women with prior history of unexplained infertility were included as group A (study group). A Second set of 70 fertile control group were included as group B (control group). Results: Our study indicated that 25(OH) vitamin-D was significant lower in unexplained infertility group than control group (according to vitamin D level 39 out of 70 in unexplained infertility patient (55.7) had deficiency, while 30(42.9%) had insufficiency and 1(1.4) had sufficiency, in comparison to control group 21(30.0%) had deficiency, while 43(61.4) had insufficiency and 6(8.6%) had sufficiency), there were no significant correlation between 25(OH) vitamin D and age and BMI. Conclusion: Vitamin-D deficiency had a role in unexplained infertility, nevertheless it is not a good diagnostic test. Unexplained infertility is multifactorial; Vit-D is only one of many factors/ theories.

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Section: Discussionsupporting

confidence: 90%

Association Between Vitamin D Deficiency and Unexplained Infertility

Ramy,

Rafaat,

Abdel Hameed

et al. 2023

Evidence Based Women's Health Journal

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“…Reseptor vitamin D (VDR) memicu peningkatan konsentrasi Ca2+ intraseluler secara cepat melalui pelepasan inositol triphosphate (IP3)-mediated Ca2+ dari intracellular IP3-receptor-gated calcium store pada leher spermatozoa manusia. 25…”

Section: Pendahuluanunclassified

Hubungan Kadar Vitamin D Serum dengan Konsentrasi, Motilitas dan Morfologi Sperma pada Pria Subfertil di Klinik Teknologi Reproduksi Berbantu Aster Rumah Sakit Dr. Hasan Sadikin Bandung

Rahma¹,

Permadi²,

Rachmawati³

et al. 2020

Obgynia

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Untuk menganalisis hubungan kadar vitamin D dengan kualitas sperma pada pria subfertil, serta membandingkan kualitas sperma berdasarkan klasifikasi kadar vitamin D serum pada pria normospermia dan pria oligoasthenoteratospermia. Metode: Penelitian ini merupakan penelitian yang bersifat observasional analitik dengan rancangan studi potong lintang. Subjek penelitian adalah pria subfertil yang berusia 20-50 tahun, dibagi menjadi 2 kelompok, yaitu 30 pasien normospermia dan 16 pasien oligoasthenoteratospermia berdasarkan berdasarkan kriteria World Health Organization 2010. Penelitian dilakukan di Klinik Teknologi Reproduksi Berbantu Aster, RSUP Dr. Hasan Sadikin Bandung. Analisis data menggunakan analisis korelasi rank Spearman Hasil: Pada penelitian ini didapatkan korelasi positif antara kadar vitamin D dan motilitas sperma (r = 0,639, p = < 0,001), tetapi tidak didapatkan korelasi pada konsentrasi dan morfologi sperma (p>0,05). Perbedaan yang bermakna didapatkan antara kadar vitamin D pada kelompok normospermia dan oligoasthenoteratospermia dengan nilai p<0,05. Pada perbandingan kualitas sperma berdasarkan klasifikasi kadar vitamin D hanya motilitas sperma saja yang memiliki perbedaan bermakna dengan nilai p<0,05. Simpulan: Terdapat hubungan yang bermakna antara kadar vitamin D serum dan motilitas sperma.

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Section: Pendahuluanunclassified

Hubungan Kadar Vitamin D Serum dengan Konsentrasi, Motilitas dan Morfologi Sperma pada Pria Subfertil di Klinik Teknologi Reproduksi Berbantu Aster Rumah Sakit Dr. Hasan Sadikin Bandung

Rahma,

Permadi,

Rachmawati

et al. 2020

Obgynia

View full text Add to dashboard Cite

Tujuan: Untuk menganalisis hubungan kadar vitamin D dengan kualitas sperma pada pria subfertil, serta membandingkan kualitas sperma berdasarkan klasifikasi kadar vitamin D serum pada pria normospermia dan pria oligoasthenoteratospermia.Metode: Penelitian ini merupakan penelitian yang bersifat observasional analitik dengan rancangan studi potong lintang. Subjek penelitian adalah pria subfertil yang berusia 20-50 tahun, dibagi menjadi 2 kelompok, yaitu 30 pasien normospermia dan 16 pasien oligoasthenoteratospermia berdasarkan berdasarkan kriteria World Health Organization 2010. Penelitian dilakukan di Klinik Teknologi Reproduksi Berbantu Aster, RSUP Dr. Hasan Sadikin Bandung. Analisis data menggunakan analisis korelasi rank SpearmanHasil: Pada penelitian ini didapatkan korelasi positif antara kadar vitamin D dan motilitas sperma ( r = 0,639, p = < 0,001), tetapi tidak didapatkan korelasi pada konsentrasi dan morfologi sperma ( p>0,05). Perbedaan yang bermakna didapatkan antara kadar vitamin D pada kelompok normospermia dan oligoasthenoteratospermia dengan nilai p<0,05. Pada perbandingan kualitas sperma berdasarkan klasifikasi kadar vitamin D hanya motilitas sperma saja yang memiliki perbedaan bermakna dengan nilai p<0,05.Simpulan: Terdapat hubungan yang bermakna antara kadar vitamin D serum dan motilitas sperma.Correlation Of Vitamin D Serum Level With Concentration, Motility, And Morphology Of Spermatozoa Subfertil In Assisted Reproductive Technology Aster Clinic Hasan Sadikin Hospital BandungAbstractObjective: This study aims to analyze the relationship of vitamin D levels with sperm quality in subfertile men, as well as comparing sperm quality based on vitamin D serum levels classification in normospermic men and oligoasthenoteratospermia men.Method: This study is an analytic observasional with cross sectional design. Research subjects were subfertile men aged 20-50 years divided into 2 groups, consisting of 30 patients with normospermic and 16 patients with oligoasthenoteratospermia based on World Health Organization 2010 criteria. The research was conducted at Assisted Reproductive Technology Aster, RSUP Dr. Hasan Sadikin Bandung. Data analysis was using Spearman’s rank correlation analytic.Result: We found a positive correlation between vitamin D levels and sperm motility (r = 0.639, p = <0.001), but no correlation was found on sperm concentration and morphology (p> 0.05). There was a significant difference between vitamin D levels in normospermic and oligoasthenoteratospermia group with p <0,05. In the sperm quality comparison based on vitamin D serum classification, only sperm motility alone had a significant difference with the value of p <0.05. It was concluded that level of vitamin D serum has positive correlation with sperm motility.Key word: subfertile, vitamin D, sperm quality

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Role of sunshine vitamin D sufficiency in male and female infertility

Cited by 7 publications

References 16 publications

Association Between Vitamin D Deficiency and Unexplained Infertility

Association Between Vitamin D Deficiency and Unexplained Infertility

Hubungan Kadar Vitamin D Serum dengan Konsentrasi, Motilitas dan Morfologi Sperma pada Pria Subfertil di Klinik Teknologi Reproduksi Berbantu Aster Rumah Sakit Dr. Hasan Sadikin Bandung

Hubungan Kadar Vitamin D Serum dengan Konsentrasi, Motilitas dan Morfologi Sperma pada Pria Subfertil di Klinik Teknologi Reproduksi Berbantu Aster Rumah Sakit Dr. Hasan Sadikin Bandung

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