Role of Synbiotics in Improvement of Feed Tolerance and Weight Gain in the Newborns

Abstract

Objective: To study the effect of Synbiotics on weight gain and feed tolerance of newborns. Methods: This prospective interventional trial included 50 newborns treated with a dietary supplement containing Synbiotics in addition to the routine treatment and 48 newborns served as control without Synbiotics supplement. The primary outcome was weight gain and feed tolerance. Results: Newborns in the Synbiotics group reached the full feeds earlier as compared to those in Control group (7.5 ± 4.26 days Vs 14.02 ± 7.88 days p=0.532) along with better weight gain(14.61 ± 9.6 grams per day Vs 2.97 ± 3.81 grams per day p=0.0000001). Conclusions: Newborns receiving Synbiotics are more likely to reach full feeds earlier and show better weight gain.

To study the role of probiotics in the prevention of necrotizing enterocolitis in preterm neonates

“…The study by Hartel et al showed that infants treated with probiotics had improved daily weight gain (20.8±6.6 vs 22.2±5.2, p<0.001). 17 Ravindra Sonawane et al observed better weight gain among newborns receiving synbiotics (14.61±9.6 grams per day vs 2.97±3.81 grams per day, p=0.0000001) 18.…”