Role of the third intracellular loop in the subtype-specific internalization and recycling of muscarinic M2 and M4 receptors

Abstract

Muscarinic M2, M4, and M2-M4 chimera receptors were transiently expressed in HEK-293 tsA201 cells, and agonist-dependent internalization of these receptors and recycling of internalized receptors were examined by measuring the amount of cell-surface receptors as [