We present a flexible thermoelectric (TE) generator with titanium dioxide (TiO 2), antimony (Sb), and tellurium (Te) powders fabricated by a nanoparticle deposition system (NPDS). NPDS is a novel low-energy consumption dry-spray method that enables the deposition of inorganic materials on substrates at room temperature and under low vacuum. TiO 2 nanopowders were dispersed on a TE powder for improved adhesion between TE films and the substrate. Film morphologies were investigated using fieldemission scanning electron microscopy, and the phase structure was analyzed by X-ray diffraction. A TE leg, deposited with 3 wt% TiO 2 content, had the largest Seebeck coefficient of approximately 160 µV/K. The prototype TE generator consisted of 16 TE legs linked by silver interconnects over an area of 20 × 60 mm 2. The prototype produced a voltage of 48.91 mV and a ii maximum power output of 0.18 µW from a temperature gradient of 20 K. The values are comparable to that of conventional methods. These results suggest that flexible TE generators can be fabricated by energy efficient methods, although internal and contact resistances must be decreased.