Role of Total Leukocyte Count in Diagnosis of Acute Appendicitis

Abstract

Background: Acute appendicitis is a common surgical emergency. Diagnosis may be difficult with little help from radiological and laboratory investigations. Total leukocyte count is one of the helpful investigations, being evaluated in this study. Methods: The patients presenting with right lower quadrant abdominal pain whom were diagnosed as having acute appendicitis and later underwent appendicectomy were included in the study. The preoperative leukocyte count was compared with histo-pathology findings of removed appendix. Sensitivity and specificity of TLC was calculated by standard formulas. Results: The sensitivity and specificity of TLC as calculated in this study is 76.5% and 73.7% respectively while positive predictive value is 92.5%. Conclusion: TLC although not a diagnostic criteria for acute appendicitis but still is helpful investigation in decision making.

Role of White blood cell count in Diagnostic accuracy of Acute Appendicitis

“…Still many patients present with equivocal signs and symptoms, which is one of the most challenging dilemma for surgeons. 5 An appendectomy performed on the basis of clinical diagnosis for a suspected appendicitis and it turns out to be normal appendix on the histo-pathological examination, is labeled as negative appendectomy. A negative appendectomy has a risk of postoperative complication rate of around 10%, so it is very important to correctly diagnose it in time.…”