2015
DOI: 10.1016/j.biocel.2015.05.007
|View full text |Cite
|
Sign up to set email alerts
|

Role of transcription factor Sp1 in the 4-O-methylhonokiol-mediated apoptotic effect on oral squamous cancer cells and xenograft

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
16
0

Year Published

2017
2017
2024
2024

Publication Types

Select...
7

Relationship

3
4

Authors

Journals

citations
Cited by 19 publications
(16 citation statements)
references
References 41 publications
0
16
0
Order By: Relevance
“…β-catenin is an important transcription factor involved in cell adhesion; however, Sp1 plays an important role as a basal transcription factor and represents an essential promoter in cancer cells 45 . For this reason, numerous studies of Sp1 in colon cancer cells and a variety of other cancer cells have been reported in the chemotherapeutic literature 14 15 46 47 48 , although few studies have dealt with Sp1 in terms of the anticancer effects of atmospheric-pressure plasma. The level of Sp1 expression is higher in cancer cells than in normal cells 49 .…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…β-catenin is an important transcription factor involved in cell adhesion; however, Sp1 plays an important role as a basal transcription factor and represents an essential promoter in cancer cells 45 . For this reason, numerous studies of Sp1 in colon cancer cells and a variety of other cancer cells have been reported in the chemotherapeutic literature 14 15 46 47 48 , although few studies have dealt with Sp1 in terms of the anticancer effects of atmospheric-pressure plasma. The level of Sp1 expression is higher in cancer cells than in normal cells 49 .…”
Section: Discussionmentioning
confidence: 99%
“…Conventionally, anticancer drugs that induce apoptosis have been developed as an outgrowth of chemotherapy 14 15 16 . For example, the antitumor effect of honokiol was reported for human oral squamous cancer cell lines HN22 and HSC4 16 .…”
mentioning
confidence: 99%
See 1 more Smart Citation
“…Various types of oral cancer treatment, including surgery, radiation therapy and chemotherapy, are typically used to treat patients. However, the majority of these methods are accompanied by side-effects and recurrences ( 7 ).…”
Section: Introductionmentioning
confidence: 99%
“…MHK is traditionally used in Chinese medicine for the therapy of depression and anxiety, and has been tested in experimental animal models of memory impairment or Alzheimer's disease (14,(33)(34)(35)(36). Although only a few studies investigated the effects of MHK in peripheral disorders, experimental data suggests a potential anti-tumor property of MHK in the treatment of oral squamous cell, prostate and colon carcinoma in vitro and in vivo (37)(38)(39).…”
Section: Discussionmentioning
confidence: 99%