Role of Transthoracic Doppler-Determined Coronary Flow Reserve in Patients With Chest Pain

Usefulness of the MOSAIC (measurement of stenosis by aliasing coronary flow) method using transthoracic color Doppler echocardiography in unstable angina patients

“…For the first time, Hozumi et al [1] diagnosed left anterior descending coronary artery (LAD) stenosis by this method, and this method has been applied to the circumflex [6], right [7] and three major coronary arteries [8]. Moreover, this method has been extended to evaluate coronary microvascular function in patients without significant stenosis [9][10][11][12].…”

Relationship Between Brachial Artery Flow-Mediated Dilation, Carotid Artery Intima-Media Thickness and Coronary Flow Reserve in Patients With Coronary Artery Disease

“…The CFR measurement that reflects coronary microvascular function and endothelial function of epicardial coronary arteries by doppler echocardiography, as a cheaper and easy screening test may be used as a detection method in the assessment of major epicardial coronary arteries [7, 30, 31]. A CFR of < 2 may be evidence of severe coronary artery disease.…”

Coronary flow reserve after l-thyroxine therapy in Hashimoto’s thyroiditis patients with subclinical and overt hypothyroidism

“…In that large population study, about 10% of the elderly women have been reported to develop subclinical hypothyroidism and to have thyroid autoimmunity. A more The CFR measurement that reflects coronary microvascular function and endothelial function of epicardial coronary arteries by TTDE, as a cheaper and easy screening test, may be used as a detection method in the assessment of major epicardial coronary arteries [19][20][21][22]. A CFR of \2 may be evidence of severe coronary artery disease.…”

“…Although CFR was used to be measured invasively until recently, CFR has been evaluated in echo-lab recently by using Doppler and vasodilator stress such as dipyridamole or adenosine [18][19][20][21]. By this method, impairment of CFR can be assessed before development of angiographically detectable stenosis in epicardial coronary arteries and we are able to investigate early coronary microvasculature pathology [22].…”