Many studies have documented the trends in the latitudinal position and strength of the midlatitude westerlies in the Southern Hemisphere. However, very little attention has been paid to the longitudinal variations of these trends. Here, we specifically focus on the zonal asymmetries in the southern hemisphere wind trends between 1980 and 2018. Meteorological reanalyses show a large strengthening and a statistically insignificant equatorward shift of peak near-surface winds over the Pacific, in contrast to a weaker strengthening and significant poleward shift over the Atlantic and Indian Ocean sectors. The reanalysis trends fall within the ensemble spread for historical climate model simulations, showing that climate models are able to capture the observed trends. Climate model simulations indicate that the differential movement of the peak westerlies is a manifestation of internal variability and is not a forced response. Implications of these asymmetries for other components of the climate system are discussed. Plain Language Summary The band of strong westerly winds in middle latitudes, which are often referred to as the midlatitude jet stream, influence not only temperature, regional storms, and precipitation but also the ocean circulation and amount of carbon and heat entering the oceans. In recent years, much attention has been paid to the observed strengthening and poleward shift of the Southern Hemisphere midlatitude jet. However, nearly all the focus has rested on trends in longitudinally averaged winds. Here we specifically focus on the longitudinal variations in trends over the last four decades. Observationally based data show that while the peak annual-averaged winds over the Atlantic and Indian Oceans have moved toward the South Pole, there has been an insignificant shift toward the equator for the peak winds over the Pacific Ocean. Simulations with climate models indicate that the underlying cause of this differential movement of the peak winds is internal atmospheric variability, and not a response to human activities. The longitudinal variations in the wind trends may have consequences for ocean gyre circulations and associated transport of heat and carbon into the oceans.