Role of Vitamin C in Various Cutaneous Diseases

Lever, Walter F.

doi:10.1001/archderm.1940.01490100021004

Cited by 4 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another study showed that in addition to copper, lower serum levels of zinc and selenium are also related to the occurrence of PV [ 16 , 17 ]. In the case of nutritional deficiencies, it has been shown that a relation between vitamin C deficiency and initiation of skin diseases like PV [ 18 ]. By contrast, intake of some dietary components from sources of fruits and vegetables such as thiols, tannins, isothiocyanates, and phenols from dietary sources are potential inducers of PV [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

Association of alternative healthy eating index and severity of pemphigus vulgaris: A cross-sectional study

Fallah,

Najafi,

Balighi

et al. 2023

PLoS ONE

View full text Add to dashboard Cite

Background Evidence on the association between following healthy eating and the severity of pemphigus vulgaris (PV) is scarce. Therefore, the aim of this cross-sectional study aimed to investigate the relationship between adherence to the alternative healthy eating index (AHEI) and the severity of Pemphigus vulgaris disease in adults. Methods In this hospital-based cross-sectional study, a total of 138 pemphigus vulgaris cases were studied, of which 108 had pemphigus disease area index (PDAI) ≤15, and 30 had PDAI>15. Dietary intakes were assessed using a valid 168-item food frequency questionnaire (FFQ). To calculate the AHEI, the data received from the diet were used. The subjects of this index received a score of 1–10. The final AHEI was calculated by summing the component scores. Results After adjusting for age and sex, we found that individuals with the highest AHEI score were 72% less likely to have increased PV severity compared with those with the lowest score (OR: 0.28; 95% CI: 0.08–0.92, P trend = 0.020). Further control for another potential confounder, intake energy, made the association stronger (OR: 0.24; 95% CI: 0.06–0.88, P trend = 0.017). Also, after controlling the body mass index (BMI) confounding factor, it maintained its strong relationship (OR: 0.24; 95% CI: 0.06–0.88, P trend = 0.016). Conclusion The evidence of our study shows that following the healthy eating index is associated with a reduction in the severity of pemphigus vulgaris. Prospective cohort studies are needed to confirm these findings.

show abstract

Section: Introductionmentioning

confidence: 99%

Association of alternative healthy eating index and severity of pemphigus vulgaris: A cross-sectional study

Fallah,

Najafi,

Balighi

et al. 2023

PLoS ONE

View full text Add to dashboard Cite

show abstract

Hautveränderungen bei Störungen des Vitaminstoffwechsels

Fegeler¹

1967

Grundlagen Und Grenzgebiete Der Dermatologie

View full text Add to dashboard Cite

High dietary acid load predicts severity of autoimmune skin disease: a cross-sectional study

Fallah,

Azad,

Najafi

et al. 2024

Sci Rep

View full text Add to dashboard Cite

No previous study has examined the association of an acid-base imbalanced diet to autoimmune bullous disease. The present study aimed to investigate the association between dietary acid load (DAL) as either potential renal acid load (PRAL) and net endogenous acid production (NEAP) intake on the odds of high-severity Pemphigus Vulgaris (PV) disease in adult Iranian patients to fill this gap. A cross-sectional study was conducted on 138 patients, aged 18–65 years with confirmed diagnoses of PV in a referral university center for autoimmune bullous diseases. The dietary intakes of all patients during the last year before enrollment in the study were assessed using a 168-item semi-quantitative food frequency questionnaire. Dietary acid load was calculated based on the PRAL and NEAP scores. To assess PV severity, the pemphigus disease area index (PDAI) score was used. Logistic regression was used to evaluate the association between DAL and PDAI. A positive association was observed between PRAL and PDAI score in the crude (adjusted R 2 = 0.088, B = 6.88, P < 0.0001) and all other adjusted models, as well as the crude model for NEAP (adjusted R 2 = 0.037, B = 4.72, P = 0.013). In terms of adherence to NEAP and PRAL, those in the top tertile of PRAL and NEAP had a higher vulnerability for severe PV in unadjusted (OR = 5.18, 95% (CI) 2.19–12.25) and (OR = 2.48, 95% (CI) 1.08–5.68) respectively. In the present study, we found a significant direct association between DAL and severity of disease in PV patients. Further studies are required to confirm these findings.

show abstract

Role of Vitamin C in Various Cutaneous Diseases

Cited by 4 publications

References 10 publications

Association of alternative healthy eating index and severity of pemphigus vulgaris: A cross-sectional study

Association of alternative healthy eating index and severity of pemphigus vulgaris: A cross-sectional study

Hautveränderungen bei Störungen des Vitaminstoffwechsels

High dietary acid load predicts severity of autoimmune skin disease: a cross-sectional study

Contact Info

Product

Resources

About