Background: Organizational-related stress is a global issue. Organizational Role Stress (ORS) is described as “The emotional, cognitive, behavioural, and physiological reaction to aversive and noxious aspects of work, work environments, and work organizations.” Studies have indicated that when compared to other professions, Health Care Workers (HCWs) are at higher risk of organizational stress with rising job expectations. Aim & Objective: To determine the Organizational Role of Stress among Health Care Workers working in Sub Health Centres of Raipur District Chhattisgarh and its association with sociodemographic characteristics. Methods and Material: A descriptive cross-sectional study among 113 HCWs was done by using a self-administered questionnaire, using Pareek’s ORS Scale to determine 10 dimensions of Role Stress such as Inter-Role Distance, Role Stagnation, Role Expectation Conflict, Role Erosion, Role Overload, Role Isolation, Personal Inadequacy, Self-Role Distance, Role Ambiguity, and Resource Inadequacy. HCWs were selected by simple random sampling. Results: Role overload was the cause of the greatest role stress level among HCWs. Levels of ORS were observed to have a statistically significant association with higher among female HCWs, among unmarried, among nuclear families, those who were educated below 10th standard, and among the upper class. Conclusions: This study's findings need administrators and policymakers to establish an attractive working environment to reduce the side effects and effects of role stress and boost the HCWs' productivity.