Roles of dopamine receptors in mediating acute modulation of immunological responses in Macrobrachium rosenbergii

Chang, Zhong–Wen; Ke, Zhi-Han; Chang, Chin‐Chyuan

doi:10.1016/j.fsi.2015.12.046

Cited by 25 publications

(4 citation statements)

References 52 publications

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“…Oxyhemocyanin is a blue pigment formed by the oxygen and hemocyanin in ratio 1:2 (Cheng et al, 2013), while hemocyanin is a glycoprotein contained copper and it is usually found in the hemolymph (Zheng et al, 2016). The declined oxyhemocynanin disrupted the metabolism, osmoregulation, and resporation system which later caused stress and unable to adapt to the environment (Chang et al, 2016). Adding the previous statement, Camacho-Jimenez et al (2017) reported that a 2 × 10 -6 mol of dopamine potentially controlled the osmoregulation system in the whiteleg shrimp Litopenaeus vannamei.…”

Section: Discussionmentioning

confidence: 94%

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Wijaya

Sudrajat

Imron³

2020

Jurnal Akuakultur Indonesia

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Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormonePerforma reproduksi dan pertumbuhan pascapenghambatan pematangan gonad udang galah betina secara hormonal menggunakan dopamin dan medroxyprogesteron ABSTRACT One of the main problem in giant river prawn (GFP) culture is early gonadal maturation in female resulting a reduced growth performance. This problem cause economic losses. When GFP at gonadal maturation, somatic growth will be inhibited because energy is used for reproduction. A factorial experimental design using two factors, namely dopamine and medroxyprogesterone, with each factor consist of three levels was applied. Three dopamine levels were 0, 10 -5 mol/shrimp, and 10 -10 mol/shrimp, while the medroxyprogesterone levels were 0, 75 mg/1.5 mL/bodyweight, and 150 mg/3 mL/bodyweight with a density 15 individual/tank. The utilization of dopamine and medroxyprogesterone in GFP (initial bodyweight : 11.27 ± 0.97 g) through injection at the third periopod was done three times at week 0, 2 nd , and 4 th with two weeks interval. The results showed that hormone inhibitor treatments affected both growth and reproductive performances in female GFP. The treated individuals showed a lower gonadal maturity indicator values and faster growth rate than control. Gonadal maturity, as shown by gonad histology, in all treatments were lower (previtelogenic and vitellogenic stages) than that in control which is in mature stage. Estradiol concentration premix dopamine 10 -10 mol/shrimp and medroxyprogesterone 150 mg/3 mL/ bodyweight treatments are lower than control. In conclusion, dopamine and medroxyprogesterone administration could suppres GSI and gonad development, and also increase growth rate. ABSTRAKKematangan gonad dini induk udang galah Macrobrachium rosenbergii betina dapat merugikan. Saat udang matang gonad, pertumbuhan somatik terhambat disebabkan energi untuk pertumbuhan akan digunakan untuk reproduksi. Penelitian ini bertujuan mengevaluasi penggunaan hormon dopamin dan medroxyprogesterone sebagai penghambat pematangan gonad. Penelitian ini menggunakan rancangan acak lengkap faktorial dengan dua perlakuan yaitu pemberian dopamin dan medroxyprogesterone. Dosis dopamin yang digunakan yaitu 0, 10 -5 mol/udang, dan 10 -10 mol/udang, sedangkan medroxyprogesterone dengan dosis 0, 75 mg/1,5 mL/bobot udang, dan 150 mg/3 mL/bobot udang dengan kepadatan 15 ekor/bak. Udang galah betina (bobot awal:11,27 ± 0,97 g) diberi perlakuan berupa dopamin dan medroxyprogesterone sebanyak tiga kali pada minggu ke-0, 2, dan 4 dengan interval waktu dua minggu sekali. Hasil penelitian ini menunjukan perlakuan dopamin dan medroxyprogesterone memiliki nilai indeks kematangan gonad (IKG) yang rendah dan laju pertumbuhan yang lebih cepat dibandingkan kontrol. Histologi gonad pada semua perlakuan berada pada tahap previtellogenic dan vitellogenic dibandingkan kontrol yang berada pada tahap mature. Konsentrasi estradiol pada perlakuan pre...

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Section: Discussionmentioning

confidence: 94%

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Wijaya

Sudrajat

Imron³

2020

Jurnal Akuakultur Indonesia

View full text Add to dashboard Cite

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“…into promoting type receptor and inhibiting type receptor, in which DA1R is promoting type receptor that activates cAMP to transmit signalling in Marbled crayfish (52) , P. monodon (53) and Macrobrachium rosenbergii (54) , while DA4R is inhibiting type receptor that inhibits cAMP but activates DAG to transmit signalling in L. vannamei (8,24,38) . The expression patterns of GC, DA1R and DA4R in haemocytes and gills of L. vannamei under salinity and ammonia-N stress were similar to this study (24,25,29) .…”

Section: Discussionmentioning

confidence: 99%

Effects of crustacean hyperglycaemic hormone RNA interference on regulation of glucose metabolism in Litopenaeus vannamei after ammonia-nitrogen exposure

et al. 2021

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To unveil the adaptation of Litopenaeus vannamei to elevated ambient ammonia-N, crustacean hyperglycemic hormone (CHH) was knocked down to investigate its function in glucose metabolism pathway under ammonia-N exposure. When CHH was silenced, haemolymph glucose increased significantly during 3-6 h, decreased significantly during 12-48 h, and recovered to the control groups’ level at 72 h. After CHH knockdown, DA contents reduced significantly during 3-24 h, which recovered after 48 h. Besides, the expressions of GC and DA1R in the hepatopancreas decreased significantly, while DA4R increased significantly. Correspondingly, the contents of cAMP, cGMP and DAG and the expressions of PKA, PKG, AMPKα and AMPKγ were significantly downregulated, while the levels of PKC and AMPKβ were significantly upregulated. The expressions of CREB and GLUT2 decreased significantly, while GLUT1 increased significantly. Moreover, glycogen content, glycogen synthase and glycogen phosphorylase activities in hepatopancreas and muscle were significantly increased. Furthermore, the levels of key enzymes HK, PK and PFK in glycolysis, rate-limiting enzymes CS in TCA, and critical enzymes PEPCK, FBP and G6P in gluconeogenesis were significantly decreased in hepatopancreas. These results suggest that CHH affects DA, and then they affect their receptors respectively to transmit glucose metabolism signals into the hepatopancreas of L. vannamei under ammonia-N stress. CHH acts on cGMP-PKG-AMPKα-CREB pathway through GC, and CHH affects DA to influence cAMP-PKA-AMPKγ-CREB and DAG-PKC-AMPKβ-CREB pathways, thereby regulating GLUTs, inhibiting glycogen metabolism and promoting glycolysis and gluconeogenesis. This study contributes to further understand glucose metabolism mechanism of crustacean in response to environmental stress.

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“…Similarly, the catecholamine dopamine (DA) is reported to affect the immunity of crustaceans, as it suppresses the immune response of shrimp ( P. monodon and M. rosenbergii ) as well as increase their susceptibility to bacteria ( Lactococcus garvieae and Photobacterium damsela ) infection. DA receptors also couple with G protein to activate the cyclic adenylate (cAMP)-PKA, DAG-PKC or CaM pathway to regulate the immune system, and modulate the activities of antioxidant enzymes ( 63 – 65 , 204 ). Thus, the enhancement of crustacean immunity after tyrosine hydroxylase silencing is achieved due to an inhibition of DA (or other catecholamines) synthesis.…”

Section: Amino Acid Metabolism and Crustacean Immunitymentioning

confidence: 99%

Modulation of Crustacean Innate Immune Response by Amino Acids and Their Metabolites: Inferences From Other Species

et al. 2020

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Aquaculture production of crustaceans (mainly shrimp and crabs) has expanded globally, but disease outbreaks and pathogenic infections have hampered production in the last two decades. As invertebrates, crustaceans lack an adaptive immune system and mainly defend and protect themselves using their innate immune system. The immune system derives energy and metabolites from nutrients, with amino acids constituting one such source. A growing number of studies have shown that amino acids and their metabolites are involved in the activation, synthesis, proliferation, and differentiation of immune cells, as well as in the activation of immune related signaling pathways, reduction of inflammatory response and regulation of oxidative stress. Key enzymes in amino acid metabolism have also been implicated in the regulation of the immune system. Here, we reviewed the role played by amino acids and their metabolites in immune-modulation in crustaceans. Information is inferred from mammals and fish where none exists for crustaceans. Research themes are identified and the relevant research gaps highlighted for further studies.

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Roles of dopamine receptors in mediating acute modulation of immunological responses in Macrobrachium rosenbergii

Cited by 25 publications

References 52 publications

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Effects of crustacean hyperglycaemic hormone RNA interference on regulation of glucose metabolism in Litopenaeus vannamei after ammonia-nitrogen exposure

Modulation of Crustacean Innate Immune Response by Amino Acids and Their Metabolites: Inferences From Other Species

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