2023
DOI: 10.3892/ol.2023.14117
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Roles of estrogen receptor α in endometrial carcinoma (Review)

Yidong Ge,
Xiaoqi Ni,
Jingyun Li
et al.

Abstract: Endometrial carcinoma (EC) is a group of endometrial epithelial malignancies, most of which are adenocarcinomas and occur in perimenopausal and postmenopausal women. It is one of the most common carcinomas of the female reproductive system. It has been shown that the occurrence and development of EC is closely associated with the interaction between estrogen (estradiol, E2) and estrogen receptors (ERs), particularly ERα. As a key nuclear transcription factor, ERα is a carcinogenic factor in EC. Its interaction… Show more

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