2024
DOI: 10.1080/19490976.2024.2320280
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Roles of microbiota in pancreatic cancer development and treatment

Mariana Santos Cruz,
Joseph Tintelnot,
Nicola Gagliani

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor prognosis. This is due to the fact that most cases are only diagnosed at an advanced and palliative disease stage, and there is a high incidence of therapy resistance. Despite ongoing efforts, to date, the mechanisms underlying PDAC oncogenesis and its poor responses to treatment are still largely unclear. As the study of the microbiome in cancer progresses, growing evidence suggests that bacteria or fungi might be key players both in P… Show more

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Cited by 8 publications
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References 143 publications
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