Room-temperature conversion of CO₂ into quinazoline-2,4(1H,3H)-dione using deep eutectic solvents at atmospheric pressure with high efficiency

Abstract

High efficient and sustainable conversion of CO2 into quinazoline-2,4(1H,3H)-dione at room temperature and atmospheric pressure is challenging. Deep eutectic solvents (DESs) are considered as the green solvents of the 21st...

Unexpectedly Superhigh Toxicity of Superbase-Derived Deep Eutectic Solvents albeit High Efficiency for CO2 Capture and Conversion

“…Mu and co-workers found that superbase-derived DESs could be volatilized after efficient capture CO 2 . Furthermore, Mu and co-workers found that DBN-based DESs could catalyze CO 2 into quinazoline-2,4­(1H,3H)-dione with the yield of >99% at room temperature and atmospheric pressure . Fu et al found that ethylene glycol-assisted DBU-based DESs could capture 0.163 w/w CO 2 at 40 °C and 1 atm .…”

“…1 Furthermore, Mu and co-workers found that DBN-based DESs could catalyze CO 2 into quinazoline-2,4(1H,3H)-dione with the yield of >99% at room temperature and atmospheric pressure. 46 (NMR), and density functional theory calculation. 48 Xue and co-workers found that superbase-derived DESs containing DBN and pyridine N-oxide/2-picoline-N-oxide could dissolve cellulose with the solubility of 14.1 wt % 70 °C.…”

Benoxazolone-based ionic liquid catalyzed C–S bond construction for synthesis of benzothiazoles from 2-aminothiophenols and CO2 under ambient conditions

“…1 Additionally, CO 2 can also be regarded as a renewable C1 resource due to its inherent characteristics such as nontoxicity, low cost, abundant reserves, easy accessibility, etc. 2 Thus, various value-added chemicals and fuels including methanol, 3 hydrocarbons, 4 cyclic carbonates, 5 quinazolinediones, 6 amides 7 and others have been produced using CO 2 as a C1 feedstock, which offer green reaction routes for these organic syntheses from the viewpoint of green chemistry and sustainable development. However, since CO 2 is thermodynamically stable and kinetically inert, metal catalysts and harsh reaction conditions are generally required for its transformation.…”

Tuning Ionic Liquid-Based Catalysts for CO2 Conversion into Quinazoline-2,4(1H,3H)-diones

“…Among these chemicals, quinazoline-2,4(1 H ,3 H )-diones, regarded as pharmaceutical intermediates with a wide range of biological activity, have been successfully synthesized from CO 2 and o -aminobenzonitriles. This reaction is an atom-economical route, and it has been widely investigated using kinds of catalysts, such as metal oxides, [ 4 , 5 ] inorganic/organic supported/grafted catalysts, [ 6 , 7 , 8 , 9 ] organic bases, [ 10 , 11 , 12 , 13 , 14 , 15 ] water, [ 16 ] etc. However, most of these reaction systems have drawbacks, such as high CO 2 pressures, high temperatures, high catalyst loadings, long reaction times, and difficulties in recycling the catalysts.…”