Room temperature diazotization and coupling reaction using a DES–ethanol system: a green approach towards the synthesis of monoazo pigments

Kamble, Sujit S.; Shankarling, Ganapati S.

doi:10.1039/c9cc01114e

Cited by 9 publications

(6 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4 Hz). The chemical shift of 6ʹ-H in 3h is similar to that noted for the related dye derived from the coupling of 2-fluoraniline with 2-naphthol reported by Shankarling et al [20] Additionally, the chemical shift of the signal for 6ʹ-H is, to some extent, influenced by the nature of the ortho-substituent, for example with a MeO substitue nt the signal for 6ʹ-H of 3g resonates further upfield than in 3h at  7.99 but with a NO2 substitue nt 6ʹ-H of 3f is deshielded and resonates at  8.26; the latter signal is in agreement with data reported for (Z)-1-[2-(2-nitrophenyl)hydrazineylidene]naphthalen-2(1H)-one in a detailed NMR investigation by Lyčka. [21].…”

Section: Discussionsupporting

confidence: 85%

Ketohydrazone dyes derived from 4-morpholino-2-naphthol and ortho-substituted anilines: Further examination of the hyperchromism induced by the 4-morpholino-2-naphthol moiety

et al. 2021

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 85%

Ketohydrazone dyes derived from 4-morpholino-2-naphthol and ortho-substituted anilines: Further examination of the hyperchromism induced by the 4-morpholino-2-naphthol moiety

et al. 2021

View full text Add to dashboard Cite

“…In excess acid, N-nitrosamine can be converted into a diazohydroxide by protonation and deprotonation. The final step is forming the nitrogen-nitrogen triple bond accompanied by the expulsion of water to produce diazonium salt [22].…”

Section: Figurementioning

confidence: 99%

Determination of the optimum concentration of the coupling agent in chloramphenicol analysis

Khudzaifah¹,

Basukiwardojo²

2022

World J. Adv. Res. Rev.

View full text Add to dashboard Cite

The aim of this research is to determine the optimum concentration of the coupling agent used in chloramphenicol analysis, then calculate the limit of detection of that photometric reaction. Chloramphenicol is a colorless compound that is often abused in animals whose products are consumed by humans. Chloramphenicol has side effects on the human body. So, chloramphenicol must be analyzed. To facilitate the analysis process, chloramphenicol must be converted into colored compounds called azo compounds. To make azo compounds must go through the process of reduction, diazotization, and coupling. A coupling agent is an important compound that played a role in an azo compound formation and was analyzed using UV-Vis spectrophotometer. This research, used N-(-1-Naphthyl) ethylenediamine dihydrochloride (NEDA) with variations concentrations of 0.1%, 0.3%, 0.5% at 565 nm. The optimum coupling concentration that gives maximum absorbance was 0.1%. The detection limit (LOD) obtained by using the optimum coupling is 0.0498 μg/mL, the limit of quantitation (LOQ) is 0.1660 μg/mL, the sensitivity value is 0.1425, and a correlation coefficient (R2) of 0.999 with a concentration range of chloramphenicol is 0,14 - 1,4 ppm.

show abstract

“…Despite the increasing use of DESs in organic synthesis [ 4 , 5 , 6 ], they have scarcely been utilized in the reactions of diazonium salts. In fact, the literature shows only three very recent examples, where DESs are employed as innocent solvents [ 7 , 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Copper-Free Halodediazoniation of Arenediazonium Tetrafluoroborates in Deep Eutectic Solvents-like Mixtures

et al. 2022

View full text Add to dashboard Cite

Deep Eutectic Solvent (DES)-like mixtures, based on glycerol and different halide organic and inorganic salts, are successfully exploited as new media in copper-free halodediazoniation of arenediazonium salts. The reactions are carried out in absence of metal-based catalysts, at room temperature and in a short time. Pure target products are obtained without the need for chromatographic separation. The solvents are fully characterized, and a computational study is presented aiming to understand the reaction mechanism.

show abstract

Room temperature diazotization and coupling reaction using a DES–ethanol system: a green approach towards the synthesis of monoazo pigments

Abstract: Synthesis of a stable diazonium salt at room temperature followed by the synthesis of monoazo pigments using DES–ethanol system.

Cited by 9 publications

References 29 publications

Ketohydrazone dyes derived from 4-morpholino-2-naphthol and ortho-substituted anilines: Further examination of the hyperchromism induced by the 4-morpholino-2-naphthol moiety

Ketohydrazone dyes derived from 4-morpholino-2-naphthol and ortho-substituted anilines: Further examination of the hyperchromism induced by the 4-morpholino-2-naphthol moiety

Determination of the optimum concentration of the coupling agent in chloramphenicol analysis

Copper-Free Halodediazoniation of Arenediazonium Tetrafluoroborates in Deep Eutectic Solvents-like Mixtures

Contact Info

Product

Resources

About