Ropivacaine Versus Bupivacaine-Lignocaine Mixture in Peribulbar Block- A Comparative Study

Varshney, Rahul; Sharma, Vimlesh; Palaria, Urmila; Kashyap, Anshika

doi:10.14260/jemds/2017/799

Cited by 5 publications

(8 citation statements)

References 13 publications

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“…Similar to our study, Varshney et al 8 reported better postoperative anesthesia with ropivacaine as compared to combined lignocaine and bupivacaine. However, this study was limited only to macular surgeries, where the globe manipulation was minimal.…”

Section: Limitation Of the Studysupporting

confidence: 91%

“…Varshney et al concluded that ropivacaine was a good alternative for peribulbar anesthesia compared to bupivacaine/lignocaine as it has a faster onset and lesser toxic effects than other comparable local anesthetic agents. 8 Peribulbar block involves the administration of local anesthetic into the muscle orbicularis oris both above and below the orbit. This technique blocks the ciliary nerves in addition to CN III and VI; however, the optic nerve remains unobstructed during this form of local anesthesia.…”

Section: Discussionmentioning

confidence: 99%

“…In a similar vein, Trivedi et al compared the peribulbar anesthetic efficacy of ropivacaine and a mixture of lidocaine and bupivacaine when performing vitreoretinal (VR) surgery. 8 In addition, there have been reports of its vasoconstrictive properties, which aid in the reduction of IOP through the inhibition of intraocular blood volume. 9 This prospective, comparative analysis of 0.5% bupivacaine and 0.5% ropivacaine in the peribulbar block for cataract surgery was motivated by the aforementioned reports.…”

Section: Introductionmentioning

confidence: 99%

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Comparative study between 0.5% bupivacaine versus 0.5% ropivacaine in peribulbar anesthesia for cataract surgery

Neel Rana,

Shruti M. Shah,

Shrutika Parag Ved

et al. 2024

Asian J Med Sci

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Background: For intraocular surgery, the optimal local anesthetic agent must have a rapid onset of action and a sufficient duration of effect so as to enable a painless, motionless procedure without prolonging akinesia. Aims and Objective: This prospective, comparative observational study compares ropivacaine and 0.5% bupivacaine for cataract surgery peribulbar block. Hyaluronidase is utilized in both groups because it promotes local anesthetic diffusion. Material and Methods: Present prospective, observational, comparative study performed at the Department of Anesthesia Tertiary Care Teaching Institute of India for the duration of 1 year. All eligible patients were allocated in two groups as GROUP B and GROUP R. GROUP B: 10 mL of 0.5% bupivacaine and 15 I.U./mL of hyaluronidase. GROUP R: 10 mL of 0.5% ropivacaine and 15 I.U./mL of hyaluronidase. Patients were assessed for sensory block, eyelid, and ocular movements at an interval of 2 min, and Visual Analog Scale score for pain assessment. Results: Age and gender did not differ significantly between the two study groups, according to the findings. Comparable and similar patient characteristics distinguished the two study groups. (P>0.05). The difference in onset of eyelid motor blockade between the two groups was not statistically significant. The difference in the onset of motor blockade [ocular movement] between the two groups was not statistically significant (P>0.05). (P>0.05) Analgesia duration differed significantly between the two groups in a statistical sense. Ropivacaine exhibits a significantly prolonged duration of analgesic effect than bupivacaine (P≤0.05). Conclusion: Peribulbar block utilizing 0.5% ropivacaine is a more favorable and secure option for a local anesthetic that effectively extends postoperative pain alleviation, in comparison to the use of 0.5% bupivacaine.

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Section: Limitation Of the Studysupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparative study between 0.5% bupivacaine versus 0.5% ropivacaine in peribulbar anesthesia for cataract surgery

Neel Rana,

Shruti M. Shah,

Shrutika Parag Ved

et al. 2024

Asian J Med Sci

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“…Varshney et al . [ 23 ] comparing ropivacaine 0.75% with a 1:1 mixture of bupivacaine 0.5% and lidocaine 2%, reported onset of complete akinesia (motor block) as 15 min, whereas we observed the duration of the onset of motor block as 2.8 ± 1.2 min, 2.9 ± 1.2 min, 2.9 ± 1.3 min, and 2.7 ± 1.9 min, respectively, in our four groups. The faster onset of the block noted in our study clearly indicates the role of DMT and hyaluronidase used in our patients.…”

Section: Discussionmentioning

confidence: 99%

A prospective, randomized, triple-blind comparative study of ropivacaine-dexmedetomidine versus ropivacaine alone in peribulbar blocks

Arepalli

Moolagani

Prathi

et al. 2022

Journal of Anaesthesiology Clinical Pharmacology

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Background and Aims: Bupivacaine and lidocaine mixtures are the commonly used local anesthetic drugs for the peribulbar blocks. Because of its safe anesthetic profile, ropivacaine is being investigated as an alternative agent. Several centers have evaluated the effect of the addition of an adjuvant like dexmedetomidine (DMT) to ropivacaine in enhancing the block characteristics. We proposed to evaluate the effect of the addition of DMT to ropivacaine versus a control group not having DMT as adjuvant. Material and Methods: A prospective, randomized comparative study was conducted on a total of 80 patients attending our hospital for cataract surgeries. Patients were allocated into four groups of 20 each ( n = 20) and peribulbar blocks were given 6 mL of 0.75% ropivacaine in group R and 6 mL of 0.75% ropivacaine plus 10 μg, 15 μg, and 20 μg DMT, respectively, in groups RD1, RD2, and RD3. Results: When DMT was used as an adjunct to ropivacaine, there was a prolongation of the duration of the sensory block. Conclusion: In peribulbar blocks, 6 mL of ropivacaine 0.75% produces satisfactory block characteristics, and the addition of 10 μg, 15 μg, or 20 μg of DMT as an adjuvant to ropivacaine 0.75% had the effect of significantly prolonging the duration of the sensory block, which is directly proportional to the dose of DMT employed. However, 20 μg of DMT added as an adjuvant to ropivacaine 0.75% appears to be the optimal dose, as this anesthetic drug mixture provides maximum prolongation of the sensory block besides providing satisfactory operating conditions, acceptable sedation levels, and stable hemodynamic parameters.

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“…[ 6 7 8 ] Although the efficacy and safety of ropivacaine for peribulbar and retrobulbar anesthesia during cataract surgery have been extensively studied, data on the use of topical ropivacaine in cataract surgery are limited. [ 9 10 11 12 13 ]…”

mentioning

confidence: 99%

Comparison between ropivacaine and bupivacaine in deep topical fornix nerve block anesthesia in patients undergoing cataract surgery by phacoemulsification

Kashyap

Varshney

Titiyal

et al. 2018

Indian J Ophthalmol

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Purpose:In this study, we intend to analyze ropivacaine and bupivacaine in various parameters during phacoemulsification under deep topical fornix nerve block (DTFNB), a known form of nerve block for phacoemulsification.Methods:This prospective randomized study was conducted on 100 patients undergoing elective cataract surgery by phacoemulsification under DTFNB. Patients were divided into two equal groups of fifty patients each, Groups B (bupivacaine) and Group R (ropivacaine). Two sponges, approximately 2 mm × 3 mm dimensions, saturated with either 0.5% bupivacaine or 0.75% ropivacaine were placed deep in the conjunctival fornices to perform the deep topical block. Both groups were evaluated for magnitude of pain and discomfort at various stages of phacoemulsification using a simple pain scoring system. The level of surgeon satisfaction, requirement for supplementary anesthesia, and surgical complications were also evaluated. Quantitative variables between the two groups were compared using unpaired t-test. Qualitative variables were correlated using Chi-square test.Results:Overall demographic parameters of patients were similar in both groups. Similar mean pain scores were found in the ropivacaine and bupivacaine groups, with no statistical significance. Surgical satisfaction and the need for supplemental anesthesia were also statistically insignificant.Conclusion:Ropivacaine is a good alternative for deep topical anesthesia as it has a better safety margin and lesser toxic effect than other comparable local anesthetic agents.

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Ropivacaine Versus Bupivacaine-Lignocaine Mixture in Peribulbar Block- A Comparative Study

Cited by 5 publications

References 13 publications

Comparative study between 0.5% bupivacaine versus 0.5% ropivacaine in peribulbar anesthesia for cataract surgery

Comparative study between 0.5% bupivacaine versus 0.5% ropivacaine in peribulbar anesthesia for cataract surgery

A prospective, randomized, triple-blind comparative study of ropivacaine-dexmedetomidine versus ropivacaine alone in peribulbar blocks

Comparison between ropivacaine and bupivacaine in deep topical fornix nerve block anesthesia in patients undergoing cataract surgery by phacoemulsification

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