ROS homeostasis during development: an evolutionary conserved strategy

Abstract

The balance between cellular proliferation and differentiation is a key aspect of development in multicellular organisms. Recent studies on Arabidopsis roots revealed distinct roles for different reactive oxygen species (ROS) in these processes. Modulation of the balance between ROS in proliferating cells and elongating cells is controlled at least in part at the transcriptional level. The effect of ROS on proliferation and differentiation is not specific for plants but appears to be conserved between prokaryotic and eukaryotic life forms. The ways in which ROS is received and how it affects cellular functioning is discussed from an evolutionary point of view. The different redox-sensing mechanisms that evolved ultimately result in the activation of gene regulatory networks that control cellular fate and decision-making. This review highlights the potential common origin of ROS sensing, indicating that organisms evolved similar strategies for utilizing ROS during development, and discusses ROS as an ancient universal developmental regulator.

SALT-RESPONSIVE ERF1 Regulates Reactive Oxygen Species-Dependent Signaling during the Initial Response to Salt Stress in Rice

“…Furthermore, salt stress increases the level of reactive oxygen species (ROS) like hydrogen peroxide (H 2 O 2 ) and superoxide anion (Bienert et al, 2006;Hong et al, 2009). Although toxic by nature, ROS have now been recognized as vital signaling components in many biological processes (Mittler et al, 2011;Schippers et al, 2012). Salt-induced ROS are predominantly represented by H 2 O 2 , both outside and inside the cell Pang and Wang, 2008).…”

Oxidant Sensing by Reversible Disulfide Bond Formation

“…Instead, ROS such as H 2 O 2 are often transiently and locally produced as part of signaling processes, reversibly modulating redox-sensitive proteins in signaling pathways. ROS-mediated signaling has recently been shown to be involved in growth, development, and differentiation processes (35), making redox-regulated disulfide bond formation an important alternative post-translational control mechanism on par with phosphorylation/dephosphorylation reactions.…”

The regulation and plasticity of root hair patterning and morphogenesis

“…Reactive forms of molecular oxygen (reactive oxygen species, ROS) are omnipresent by-products of aerobic metabolism that are highly reactive towards cellular proteins, DNA and lipids, but they also play important roles in signaling and development (Schippers et al, 2012). Signal transduction via ROS probably derived from the necessity to monitor and combat potentially harmful ROS species, which requires a sophisticated detection system.…”