ROS-mediated programmed cell death (PCD) of Thalassiosira pseudonana under the stress of BDE-47

Zhao, Yirong; Tang, Xuexi; Qu, Fangyuan; Lv, Mengchen; Liu, Qian; Li, Jun; Li, Luying; Zhang, Bihan; Zhao, Yan

doi:10.1016/j.envpol.2020.114342

Cited by 41 publications

(20 citation statements)

References 41 publications

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“…These results are well supported by previous ndings (Pradhan et al 2020c;Achary et al 2008;Kováčik and Dresler 2018;Golari et al 2018). Several mechanistic investigations have suggested that ROS induces cell death post heavy metal stress (Zhao et al 2020;Chokshi et al 2020). In response to such stressed environment, antioxidant enzymes nullify the ROS and promote cell viability.…”

Section: Discussionsupporting

confidence: 89%

Low-dose Priming of Gamma Radiation Enhanced Cadmium Tolerance in Chlamydomonas Reinhardtii by Modulating Physio-biochemical Pathways

Pradhan

Patra

Nayak

et al. 2021

Preprint

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Microalgae, the key components of aquatic environments, are executive natural biotic models for exploring genotoxic effect of heavy metals, irradiation and other external stimuli and the toxicant elimination. In the current scenario, removal of metal contaminants is a significant challenge. Recently, the effective removal of heavy metals from the aquatic environment using microalgae has gained immense intention. However, the concurrent toxicity has limited their use as bio-accumulants to reduce the concentration of heavy metals and promote heavy metal tolerance. Few studies opined that low dose priming with non-ionizing radiations, such as gamma radiation, increased heavy metal tolerance in plant as well as aquatic photosynthetic microalgae. In the present study, we have hypothesized the growth inhibitory physio-chemical properties by cadmium (Cd) in the green algae Chlamydomonas reinhardtii, and analysed the protective role of low-dose gamma radiations priming against Cd induced growth inhibition. In addition, we have specially emphasized on the mechanism of cell survival in the experimental species with effective notation to antioxidant defence system during Cd induced toxicity. Experimentally, we primed the Chlamydomonas reinhardtii with low-dose gamma radiation prior to Cd treatment. On the other hand, gamma-radiated and Cd-treated organisms were considered as positive controls. We calculated the rate of cell death, the deployment of antioxidant enzymes such as catalase (CAT), ascorbate peroxidase (APX), glutathione peroxidase (GPX), glutathione reductase (GSR), and superoxide dismutase (SOD). Furthermore, the role of oxidative stress related genes was analysed computationally to delineate their involvement in cell death/survival, suggesting that the low-dose priming of gamma radiation enhances the Cd tolerance by alterating cell/death pathways and other biochemical responses.

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Section: Discussionsupporting

confidence: 89%

Low-dose Priming of Gamma Radiation Enhanced Cadmium Tolerance in Chlamydomonas Reinhardtii by Modulating Physio-biochemical Pathways

Pradhan

Patra

Nayak

et al. 2021

Preprint

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“…Increases in ROS levels have been observed to immediately precede death (Franklin et al, 2004) and in some circumstances ROS has been directly linked to programmed cell death (Zhao et al, 2020). It is feasible that thermal acclimation involves mechanisms that serve to rebalance intracellular levels of ROS either by reducing production and/or by increasing scavenging.…”

Section: Discussionmentioning

confidence: 99%

“…These findings are in keeping with work from previous authors where phytoplankton acclimated to hyperthermic conditions were characterized by traits associated with an increased tolerance to oxidative stress, for example less susceptibility to photobleaching (Takahashi et al, 2013) or lowered intracellular levels of ROS (Buerger et al, 2020). Increases in ROS levels have been observed to immediately precede death (Franklin et al, 2004) and in some circumstances ROS has been directly linked to programmed cell death (Zhao et al, 2020). It is feasible that thermal acclimation involves mechanisms that serve to rebalance intracellular levels of ROS either by reducing production and/or by increasing scavenging.…”

Section: Discussionmentioning

confidence: 99%

Phytoplankton mortality in a changing thermal seascape

Baker

Geider

2021

Global Change Biology

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Phytoplankton growth generates half of the atmosphere's oxygen through photosynthesis, thus providing the energy that fuels pelagic food chains and playing key roles in biogeochemical cycles of oxygen, carbon and nutrient elements. Predicting spatiotemporal distributions of phytoplankton biomass and community composition heavily relies on experimental studies that document how environmental conditions influence net population growth rates, the difference between cell division rate and the death rate. Although the environmental controls on phytoplankton growth are well studied, the factors governing cell death rates remain unclear.Death rates in natural phytoplankton communities range from <0.01 to >1 day −1 (Marbá et al., 2007). Studies that have calculated death rates from measurements of cell lysis (Agustí & Duarte, 2000;Agustí et al., 1998) include contributions to death due to biotic factors such as viral infection as well as abiotic stress-induced physiological death. The death rate due to physiological stress is typically

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“…Linoleic acid promotes the caspase-3 activity as a result of oxidative stress in Karenia mikimotoi [ 94 ]. Polybrominated diphenyl ethers induce oxidative stress, activating programmed cell death signals in the diatom Thalassiosira pseudonana [ 95 ]. During blooms of Peridinium gutunense , CO 2 limitation triggers a ROS-PCD cascade reaction [ 83 ].…”

Section: Discussionmentioning

confidence: 99%

Cell Death and Metabolic Stress in Gymnodinium catenatum Induced by Allelopathy

Fernández-Herrera

Band‐Schmidt

Zenteno‐Savín

et al. 2021

Toxins

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Allelopathy between phytoplankton species can promote cellular stress and programmed cell death (PCD). The raphidophyte Chattonella marina var. marina, and the dinoflagellates Margalefidinium polykrikoides and Gymnodinium impudicum have allelopathic effects on Gymnodinium catenatum; however, the physiological mechanisms are unknown. We evaluated whether the allelopathic effect promotes cellular stress and activates PCD in G. catenatum. Cultures of G. catenatum were exposed to cell-free media of C. marina var. marina, M. polykrikoides and G. impudicum. The mortality, superoxide radical (O2●−) production, thiobarbituric acid reactive substances (TBARS) levels, superoxide dismutase (SOD) activity, protein content, and caspase-3 activity were quantified. Mortality (between 57 and 79%) was registered in G. catenatum after exposure to cell-free media of the three species. The maximal O2●− production occurred with C. marina var. marina cell-free media. The highest TBARS levels and SOD activity in G. catenatum were recorded with cell-free media from G. impudicum. The highest protein content was recorded with cell-free media from M. polykrikoides. All cell-free media caused an increase in the activity of caspase-3. These results indicate that the allelopathic effect in G. catenatum promotes cell stress and caspase-3 activation, as a signal for the induction of programmed cell death.

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ROS-mediated programmed cell death (PCD) of Thalassiosira pseudonana under the stress of BDE-47

Cited by 41 publications

References 41 publications

Low-dose Priming of Gamma Radiation Enhanced Cadmium Tolerance in Chlamydomonas Reinhardtii by Modulating Physio-biochemical Pathways

Low-dose Priming of Gamma Radiation Enhanced Cadmium Tolerance in Chlamydomonas Reinhardtii by Modulating Physio-biochemical Pathways

Phytoplankton mortality in a changing thermal seascape

Cell Death and Metabolic Stress in Gymnodinium catenatum Induced by Allelopathy

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