Rosette-forming glioneuronal tumor: an update

Anyanwu, Chikamuche; Robinson, Timothy; Huang, Jason H.

doi:10.1007/s12094-019-02179-8

Cited by 17 publications

(25 citation statements)

References 32 publications

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“…However, microcalcifications and satellite lesion are commonly found in pineal region RGNTs. Characteristic features of RGNTs have recently been review by Anyanwu et al [2] Here, we present another case of an RGNT in the pineal region, which was surgically treated at our hospital.…”

Section: Introductionmentioning

confidence: 67%

Surgical treatment of a rare rosette-forming glioneuronal tumor in the pineal region

Muhammad

Hafez

Karppinen

et al. 2020

Surgical Neurology International

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Background: Rosette-forming glioneuronal tumors (RGNTs) in the pineal region are rare. RGNTs have been described in the fourth ventricle, but rarely reported in other brain regions. Here, we report the radiological findings, surgical treatment, and short-term outcome of an RGNT found in the pineal region. Case Description: We present a case of a 22-year-old medical student with a 4-month history of headaches and diplopia. A previous magnetic resonance imaging scan revealed a mass in the pineal region, with heterogeneous contrast enhancement and hydrocephalus. Three months prior, an endoscopic biopsy and third ventriculocisternostomy were performed elsewhere; the diagnosis was neurocytoma Grade I, and radiotherapy was planned. The patient presented at our hospital for a second opinion, and we suggested surgical treatment. A near-total resection was performed in sitting position using a supracerebellar infratentorial microsurgical approach. The tumor was very soft and not well vascularized. Diplopia was initially worsened after the tumor was removed and relieved completely after 2 weeks. An 8-week follow-up examination revealed that the patient was free of symptoms. Histological analysis confirmed it was an RGNT. Conclusion: Maximal safe resection in pineal region RGNTs is a feasible and recommended treatment option.

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Section: Introductionmentioning

confidence: 67%

Surgical treatment of a rare rosette-forming glioneuronal tumor in the pineal region

Muhammad

Hafez

Karppinen

et al. 2020

Surgical Neurology International

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“…RGNT is an uncommon low-grade neuroglial tumor which is generally considered benign with slightly longer course [2]. Headache is the most recorded common symptom.…”

Section: Discussionmentioning

confidence: 99%

“…In 2007, it was classified as grade I glioma by World Health Organization (WHO). RGNT occurs most often in young women with mean age of onset at 23.57 years [2]. There are few literatures regarding the imaging features and prognosis of RGNT.…”

Section: Introductionmentioning

confidence: 99%

The rosette-forming glioneuronal tumor mimicked cerebral cysticercosis: a case report

et al. 2021

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Introduction Rosette-forming glioneuronal tumor (RGNT) is a rare variety of slow growing mixed glioneuronal tumor involving primarily fourth ventricular region. This is a comprehensive analysis of a 22-year-old woman with RGNT composed of mainly cystic components. In addition, the case showed multiple lesions located in brain parenchyma which mimicked cerebral cysticercosis. Here, we analyzed this case and listed some characteristics of RGNTs in reported literature which occurring in atypical locations for further understanding it. Case report A 22-year-old woman presented with a history of transient dizziness, nausea, and vomiting. Magnetic resonance imaging (MRI) showed multiple cystic lesions in brain parenchyma and then the patient was diagnosed with cerebral cysticercosis possibility. Empirical anti-infective therapy in addition to a follow-up post 2 weeks of MRI examination showed the lesions unchanged. Finally, a biopsy of the right cerebellar hemisphere lesions verified RGNT. Conclusion RGNT is an uncommon tumor classified as grade I glioma by World Health Organization (WHO) with slightly longer course. The imaging findings of RGNT are not specific especially in atypical areas. RGNT is rare, but we should also consider the possibility in diagnosis and differential diagnosis.

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“…A recent systematic review identified a total of 26 cases of RGNT in the literature, and 10 of those were located in or extended to the fourth ventricle. 6 Although we believe there are more cases in the literature, single reports discussing the clinical course and long-term outcomes of RGNT are still lacking.…”

Section: Therapeutic Interventionmentioning

confidence: 98%

“…Incidentally discovered lesions have been also reported. 6 While it was initially described in the fourth ventricle and cerebellum, RGNTs are increasingly reported in other locations, including the pineal gland, spinal cord, lateral ventricles, optic chiasm, hypothalamus, and pons. A recent systematic review identified a total of 26 cases of RGNT in the literature, and 10 of those were located in or extended to the fourth ventricle.…”

Section: Therapeutic Interventionmentioning

confidence: 99%

Rosette-Forming Glioneural tumor of the fourth ventricle

Abdulqader¹,

Al-Shibani²,

Alshawakeer³

et al. 2021

NSJ

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Rosette-forming glioneural tumors (RGNTs) are rare.Here, we report a case of RGNT of the fourth ventricle in an 18-year-old female. The patient presented with a 4-month history of headache and dizziness. Neurological examination showed papilledema, impaired tandem gait, and right-sided dysmetria. Radiological images showed a posterior fossa lesion in the fourth ventricle with hydrocephalus. An emergent ventriculostomy was performed followed by gross total surgical resection of the lesion. Histopathological examination confirmed the diagnosis of RGNT. The patient developed posterior fossa syndrome postoperatively which improved on follow-up. Although rare, RGNT should be considered in the differential diagnoses of posterior fossa lesions in young patients. Given its benign course, surgical resection remains the treatment of choice.

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Rosette-forming glioneuronal tumor: an update

Cited by 17 publications

References 32 publications

Surgical treatment of a rare rosette-forming glioneuronal tumor in the pineal region

Surgical treatment of a rare rosette-forming glioneuronal tumor in the pineal region

The rosette-forming glioneuronal tumor mimicked cerebral cysticercosis: a case report

Rosette-Forming Glioneural tumor of the fourth ventricle

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