Rosette-forming glioneuronal tumor of the fourth ventricle with bilateral olivary degeneration

Abstract

Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle has been recognized as a new type of glioneuronal tumor. RGNTs are typically located in the infratentorial midline with involvement of the fourth ventricle. They occasionally involve the aqueduct and/or vermis. RGNTs of unusual anatomical sites or those with unusual findings have been reported. The present case reports describe RGNT of the fourth ventricle with bilateral olivary degeneration. It is important to accumulate imaging findings and biological behaviors of RGNTs given the limited number of cases.

Rosette-forming glioneuronal tumor of the fourth ventricle

“…In the study of Shah et al ( 4 ), a majority of the lesions seemed to arise from the cerebellar vermis, without an obvious fourth ventricular element. In the case of Yasutaka et al ( 9 ), the tumor was in the midline, abutting the fourth ventricle. T2-weighted images showed several high-intensity areas within the tumor, with T1 hypointensities and no significant postcontrast enhancement.…”

“…Differential diagnoses may include pilocytic astrocytoma, medulloblastoma, ependymoma, and metastases. The age of the patient, location of the tumor, and imaging features may help in the differential diagnosis, but histopathological evaluation is necessary for definite diagnosis ( 4 , 9 ).…”

Rosette-forming glioneuronal tumour of the fourth ventricle. Not always a foreseeable development

“…This tumour appears to have a high propensity for significant adherence to the ventricular wall and infiltration into surrounding structures [12]. RGNT has a slight female predominance, and most patients are in their third decade of life [1, 6, 9].…”

“…Hypertrophic olivary degeneration was evident in our patient two years after the surgery. We have found another case reported in the literature with these radiological changes [12]. The Guillain-Mollaret triangle is a triangular circuit connecting the dentate nucleus of the cerebellum on one side with the red nucleus and inferior olive contralaterally.…”

Rosette-forming glioneuronal tumour of the fourth ventricle: case report and review of the literature

“…cifications and cystic components [4,11,13,21,23,27]. Some smaller tumour nodules may accompany these tumours [19,23,27].…”