Rosette-forming glioneuronal tumour: Imaging features, histopathological correlation and a comprehensive review of literature

Hsu, Charlie; Kwan, Gigi Nga Chi; Lau, Queenie; Bhuta, Sandeep

doi:10.3109/02688697.2012.655808

Cited by 41 publications

(21 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The shortest recurrence was seen 9 months later while the longest recurrence was seen 120 months later [4]. On the half of the patients, a postoperative neurological deficit was presented [10]. Our patient was a 33-year-old male with a long-lasting headache complaint.…”

Section: Discussionmentioning

confidence: 66%

“…The solid areas of RGNT show iso-hypointense signals on T1-weighted sequence and hyperintense signals on T2-weighted sequence on the MRI [1]. Calcification is reported on 25% of the patients [10]. Histologically, biphasic development pattern which consisted of two different cells is observed.…”

Section: Discussionmentioning

confidence: 97%

“…RGNT is a benign course tumor and when it is completely removed, the treatment is ensured. In addition, total resection may not be possible in the areas like cerebellum and brain stem [10]. In the literature, four cases with recurrence have been presented and all of them were surgically treated [4].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Rosette-Forming Glioneuronal Tumor That Did Not Recur for Six Years: A Rare Case Report

Ozkanli

2014

J Med Cases

View full text Add to dashboard Cite

Rosette-forming glioneuronal tumor (RGNT) is a central nervous system tumor type that is rarely seen and classified as grade 1 tumor by World Health Organization. They can be seen in several different locations of the brain, in the fourth ventricle. We have reviewed the English-written literature; there are 72 cases about RGNT of the fourth ventricle and most of them are of young women. On the contrary, in our case report, we analyzed a case of a 33-year-old male patient who had a long-lasting headache complaint and was diagnosed afterwards with RGNT and had no recurrence in his 6-year follow-up.

show abstract

Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Rosette-Forming Glioneuronal Tumor That Did Not Recur for Six Years: A Rare Case Report

Ozkanli

2014

J Med Cases

View full text Add to dashboard Cite

show abstract

“…Among 48 reported cases, 35 (72%) were in the fourth ventricle or vermis 2 . The second most common locations are the pineal area and tectum 1,2 and in the pineal gland with extension to the third and fourth ventricles 7 . Other posterior fossa locations such as the cerebellar hemispheres and the cerebellopontine angle are reported 2 .…”

mentioning

confidence: 99%

“…tends to be in the midline with the most common location being the fourth ventricle and aqueduct 1,2 . Among 48 reported cases, 35 (72%) were in the fourth ventricle or vermis 2 .…”

mentioning

confidence: 99%

Rosette-forming Glioneuronal Tumors in the Posterior Third Ventricle

Alnaami

Aronyk

et al. 2013

Can. J. Neurol. Sci.

View full text Add to dashboard Cite

There are no reported cases of RGNT within the third ventricle, although this tumor has also been described in the pineal region, the tectum and within the aqueduct 2 . Supratentorial localization is quite rare, with only three published: one was found in the septum pellucidum 3 , another within the optic nerve in neurofibromatosis type 1 (NF1) patient BRIEF COMMUNICATIONSwere no other neurological symptoms. On examination, his cranial nerves were all intact with no papilloedma. The remainder of the exam showed normal power, reflexes, coordination, and sensation in both upper and lower extremities.Imaging. An initial non-contrast computed tomography (CT) scan of the head demonstrated obstructive hydrocephalus. Subsequent magnetic resonance imaging (MRI) of the brain (Figure 1), confirmed hydrocephalus but also demonstrated a lesion within the posterior aspect of the third ventricle. The lesion was isointense on T1 weighted sequences and hyperintense on T2 weighted sequences with a heterogeneous enhancement pattern following administration of gadolinium.Operation. Given the progressive nature of the patient's symptoms, a decision was made to proceed with endoscopic third ventriculostomy (ETV) and biopsy of the lesion. The procedure was done using a flexible endoscope (Storz). By flexing the endoscope underneath the massa intermedia of the thalami, the tumor was visualized in the aqueductal recess, attached to the right thalamus (Figure 2). Three small biopsy samples were obtained. The endoscope was then directed

show abstract

Self‐organization of neural tissue architectures from pluripotent stem cells

Karus

Blaess

Brüstle

2014

J of Comparative Neurology

View full text Add to dashboard Cite

Despite being a subject of intensive research, the mechanisms underlying the formation of neural tissue architectures during development of the central nervous system remain largely enigmatic. So far, studies into neural pattern formation have been restricted mainly to animal experiments. With the advent of pluripotent stem cells it has become possible to explore early steps of nervous system development in vitro. These studies have unraveled a remarkable propensity of primitive neural cells to self-organize into primitive patterns such as neural tube-like rosettes in vitro. Data from more advanced 3D culture systems indicate that this intrinsic propensity for self-organization can even extend to the formation of complex architectures such as a multilayered cortical neuroepithelium or an entire optic cup. These novel experimental paradigms not only demonstrate the enormous self-organization capacity of neural stem cells, they also provide exciting prospects for studying the earliest steps of human neural tissue development and the pathogenesis of brain malformations in reductionist in vitro paradigms.

show abstract

Rosette-forming glioneuronal tumour: Imaging features, histopathological correlation and a comprehensive review of literature

Abstract: Knowledge of this tumour is of importance as they are relatively slow growing and exhibit benign histological characteristics, thus depending on its location maybe amenable to gross total resection.

Cited by 41 publications

References 26 publications

Rosette-Forming Glioneuronal Tumor That Did Not Recur for Six Years: A Rare Case Report

Rosette-Forming Glioneuronal Tumor That Did Not Recur for Six Years: A Rare Case Report

Rosette-forming Glioneuronal Tumors in the Posterior Third Ventricle

Self‐organization of neural tissue architectures from pluripotent stem cells

Contact Info

Product

Resources

About