Rotation versus non-rotation of intraocular lens for prevention of posterior capsular opacification

Joshi, Rajesh Subhash; Chavan, Shrutika A

doi:10.4103/ijo.ijo_1854_18

Cited by 11 publications

(9 citation statements)

References 19 publications

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“…In spite of this, the technique's usefulness should be evaluated in light of the possibility of PCO development and the availability of Nd: YAG capsulotomy. 25 After Nd: YAG posterior capsulotomy was performed, Ramachandra and Kuriakose, 26 found better vision and a substantial improvement in refraction, leading them to infer that a new spectacle correction was required. The present study showed that anterior chamber depth decreased gradually from pre-laser value to the last follow-up period (3 months) with statistically highly considerable variation between the two periods (p <0.001), while the central macular thickness is markedly elevated after laser, then decreased gradually till the end of the follow-up period with statistically highly significant value between the two periods (p <0.001).…”

Section: Discussionmentioning

confidence: 99%

Effect of Anterior Chamber Depth on the Development of Post YAG LASER Capsulotomy Macular Edema

Mohamed

Farag²,

Ead³

2022

Al-Azhar International Medical Journal

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Background:The most common long-term phacoemulsification cataract surgery complication is the opacification of the posterior capsule (PCO). This condition can lead to decreased vision, an impaired ability to distinguish between light and dark and the development of monocular diplopia as the result of posterior capsule opacification. Aim of The Work:To evaluate correlation between anterior chamber depth using Anterior segment OCT and assess macular thickness after YAG-LASER capsulotomy using macular OCT. Patients and Methods:The study included twenty eyes of twenty patients who had uncomplicated phacoemulsification and developed posterior capsular opacification Group(1), and 20 eyes of 20 patients who had successful phacoemulsification without complications and without PCO Group (2) were the control. They were from the Sayed Galal Hospital Ophthalmology outpatient clinic from June to December 2021 at Al-Azhar University's Faculty of Medicine. Results: The current showed that best corrected visual acuity, spherical error, and spherical equivalent improved after YAG-Laser capsulotomy and vision markedly improved at the last follow-up period with statistically highly considerable variation between the two periods (p<0.001), while the axial length decreased during the follow-up period with statistically different value between the two periods (p<0.05). Conclusion:The blood-aqueous barrier is damaged by YAG-LASER capsulotomy, releasing VEGFs and other inflammatory mediators. The anterior chamber depth was altered by inflammatory macular edema from Nd:YAG laser capsulotomy. Prophylactic therapy may not be needed.

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Section: Discussionmentioning

confidence: 99%

Effect of Anterior Chamber Depth on the Development of Post YAG LASER Capsulotomy Macular Edema

Mohamed

Farag²,

Ead³

2022

Al-Azhar International Medical Journal

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“…The IOL implanted under BSS undergoes rotation in the bag that can mechanically remove LECs. Joshi et al ,[ 9 ] in their study on rotation versus nonrotation of IOL, showed a decreased ND: YAG capsulotomy rate in the rotation group in the follow-up period of 24 months. However, they rotated the IOL by 360°.…”

Section: Discussionmentioning

confidence: 99%

“…Various modalities are available for preventing PCO, such as effective hydrodissection, cortical cleanup, equatorial epithelial lens fiber removal,[ 3 ] sealed-capsule irrig ation,[ 4 ] square-edged optic of the IOL,[ 5 6 ] ultraviolet treatment of lens epithelial cells (LECs),[ 7 ] trypan blue dye irrigation in the capsular bag,[ 8 ] and IOL rotation in the capsular bag. [ 9 ]…”

mentioning

confidence: 99%

Evaluation of posterior capsular opacification and neodymium-doped yttrium aluminum garnet capsulotomy rates in patients with hydrophilic intraocular lens implantation with and without ocular viscoelastic device

Joshi

Surwade

Rasal

2022

Indian Journal of Ophthalmology

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Purpose: To study the effect of intraocular lens (IOL) implantation with and without ocular viscoelastic device (OVD) on posterior capsular opacification (PCO) in eyes with phacoemulsification. Methods: This prospective, comparative, and randomized case series included 70 patients (140 eyes) with senile cataracts scheduled for phacoemulsification and IOL implantation in a tertiary eye c are center. One eye of each patient was randomized to one of the two groups, namely, control and OVD. After phacoemulsification, the IOL was placed in the capsular bag under balanced salt solution (BSS) in the control group, whereas the IOL was placed under OVD in the OVD group. PCO was analyzed by an independent observer at 6, 12, and 18 months under slit-lamp illumination. Results: The mean age of the participants in the two groups was 61.2 (±9.9) years. Of the total participants, 68 (48.5%) were men and 72 (51.5%) were women. The mean keratometry (K1, K2) values of the OVD (44.26 ± 1.43, 44.93 ± 1.66) and control (44.51 ± 1.74, 44.69 ± 1.49) groups were similar. The mean IOL powers of the control and OVD groups were 21.25 (±1.94) and 21.53 (±1.86), respectively ( P = 0.463). The mean best-corrected visual acuity (BCVA) of the control group at 6-, 12-, and 18-month follow-ups were 0.622 (±0.253), 0.315 (±0.203), and 0.063 (±0.163), respectively, whereas those of the OVD group were 0.592 (±0.253), 0.336 (±0.169), and 0.066 (±0.118), respectively ( P = 0.922). None of the patients had postoperative raised intraocular pressure (IOP), uveitis, or endophthalmitis . Three and four eyes in the control and OVD groups, respectively, required neodymium-doped yttrium aluminum garnet (ND: YAG) capsulotomy at study termination ( P = 0.999). Conclusion: The hydroimplantation technique of the placement of hydrophilic IOL did not reduce the PCO rate in the 18-month follow-up period. The ND: YAG capsulotomy rate did not differ between the groups.

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“…Joshi et al, assessed the effect of rotation of the implanted lens/IOL by 360 • during cataract phacoemulsification [80]. After placing/inserting the lens/IOL in the capsule, the lens was rotated 90 • using a Sinskey hook inserted through the corneal incision.…”

Section: Clinical Trialsmentioning

confidence: 99%

Posterior Capsule Opacification: A Review of Experimental Studies

Konopińska

Młynarczyk

Dmuchowska

et al. 2021

JCM

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Posterior capsule opacification (PCO) is the most common complication of cataract surgery. It causes a gradual deterioration of visual acuity, which would otherwise improve after a successful procedure. Despite recent advances in ophthalmology, this complication has not been eradicated, and the incidence of PCO can be as high as 10%. This article reviews the literature concerning the pathomechanism of PCO and examines the biochemical pathways involved in its formation and methods to prevent this complication. We also review the reported tests performed in cell cultures under laboratory conditions and in experimental animal models and in ex vivo human lens capsules. Finally, we describe research involving human eyes in the clinical setting and pharmacological methods that may reduce the frequency of PCO. Due to the multifactorial etiology of PCO, in vitro studies make it possible to assess the factors contributing to its complications and search for new therapeutic targets. Not all pathways involved in cell proliferation, migration, and contraction of the lens capsule are reproducible in laboratory conditions; moreover, PCO in humans and laboratory animals may be additionally stimulated by various degrees of postoperative reactions depending on the course of surgery. Therefore, further studies are necessary.

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Rotation versus non-rotation of intraocular lens for prevention of posterior capsular opacification

Cited by 11 publications

References 19 publications

Effect of Anterior Chamber Depth on the Development of Post YAG LASER Capsulotomy Macular Edema

Effect of Anterior Chamber Depth on the Development of Post YAG LASER Capsulotomy Macular Edema

Evaluation of posterior capsular opacification and neodymium-doped yttrium aluminum garnet capsulotomy rates in patients with hydrophilic intraocular lens implantation with and without ocular viscoelastic device

Posterior Capsule Opacification: A Review of Experimental Studies

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