Rotavirus gastroenteritis among children aged under 5 years in Al Karak, Jordan

Nafi, Omar

doi:10.26719/2010.16.10.1064

Cited by 22 publications

(16 citation statements)

References 11 publications

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“…Importantly RVGE-related hospitalizations were highest amongst children under 2 years of age, as previously observed in Middle Eastern countries such as Iran, Saudi Arabia, and Jordan 29,31,34…”

Section: Discussionsupporting

confidence: 71%

Rotavirus gastroenteritis in children under 5 years in the Kingdom of Bahrain: hospital-based surveillance

Musawi¹,

Zainaldeen²,

Shafi³

et al. 2013

CLEP

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PurposeRotavirus (RV) is the leading cause of morbidity and mortality in children under 5 years of age worldwide. This study assessed the role of RV as a cause of gastroenteritis (GE)-associated hospitalization in children, generating baseline information to evaluate the potential impact of the RV vaccine in reducing RVGE disease burden in the Kingdom of Bahrain.MethodsThis single, pediatric hospital-based surveillance study was conducted over a period of 12 months beginning April 1, 2006. A total of 314 children aged under 5 years and hospitalized due to GE were enrolled in the study, following collection of written informed consent from parents/guardians. Stool samples were tested for the presence of RV using enzyme immunoassay, and a random subset of RV-positive samples was further genotyped using reverse transcriptase-polymerase chain reaction and reverse hybridization assay.ResultsOf 314 enrolled children, 239 were included in the final analysis. RV was detected in 107 children (44.8%), mostly in the 6–23 months age group (82/107; 76.6%). RVGE occurred throughout the year, with the highest proportion occurring during April (26/42; 61.9%). G1P[8[ was the most commonly detected RV strain (10/17; 58.8%) in the limited number of samples analyzed. Vomiting and severe RVGE were more commonly observed in RV-positive than RV-negative children before hospitalization (P = 0.0008 and 0.0204, respectively).ConclusionIn our study, RV accounted for over 40% of GE-associated hospitalizations and particularly affected children under 2 years of age. These data will serve as a baseline for assessing the potential changes in the epidemiology of RV disease and for evaluating the potential impact of the introduction of RV vaccination.

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Section: Discussionsupporting

confidence: 71%

Rotavirus gastroenteritis in children under 5 years in the Kingdom of Bahrain: hospital-based surveillance

Musawi¹,

Zainaldeen²,

Shafi³

et al. 2013

CLEP

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“…As previously observed in the Eastern Mediterranean region [18][19][20][21] and Europe, 22 we found the burden of RVGE to be the highest in children younger than 2 y. More specifically, RVGE was found predominantly in the 7-12 mo age group in a study conducted in 1994 in UAE (34.8%).…”

Section: Discussionsupporting

confidence: 65%

Burden and genotyping of rotavirus disease in the United Arab Emirates

Howidi

Balhaj

Yaseen

et al. 2014

Human Vaccines & Immunotherapeutics

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“…This may be due to the geographical and climatic conditions of the region under study where the summers are not very hot because of the high altitude and hilly terrain. However, there are studies which observed relatively low rotavirus prevalence in winter season [20].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of rotavirus, norovirus and enterovirus in diarrheal diseases in Himachal Pradesh, India

et al. 2016

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Diarrheal diseases are responsible for a significant proportion of mortality and morbidity all around the globe. The contribution of viruses to gastroenteritis incidences in humans is well established. In the present study, we have studied the prevalence of rotavirus, norovirus and enterovirus in Himachal Pradesh, a north Indian state. A total of 287 (111 children and 176 adults) stool samples of gastroenteritis patients were screened for the viruses using RT-PCR method. 34.5 % samples were positive for the viral pathogens of gastroenteritis. Rotavirus was the predominant virus detected in the study with 49.5 and 14.8 % positivity in children and adults, respectively. Enterovirus was present in 5.6 % cases whereas norovirus had least prevalence (1.4 %). Co infection (rotavirus and enterovirus) was witnessed at the prevalence rate of 0.6 %. Among different age groups, the prevalence of studied viruses was highest in the children belonging to the age groups of \5 years. Rotavirus infections were found to be significantly associated with vomiting and trend of higher rates of fever and dehydration was seen in children along with diarrhea. Seasonal distribution shows circulation of diarrheagenic viruses throughout the year. This is the first report of prevalence of various diarrheagenic viruses circulating in this region. The outcome of the study from this cohort provides a baseline data which can be used to design the preventive strategies in the otherwise unexplored state of Himachal Pradesh.

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Rotavirus gastroenteritis among children aged under 5 years in Al Karak, Jordan

Cited by 22 publications

References 11 publications

Rotavirus gastroenteritis in children under 5 years in the Kingdom of Bahrain: hospital-based surveillance

Rotavirus gastroenteritis in children under 5 years in the Kingdom of Bahrain: hospital-based surveillance

Burden and genotyping of rotavirus disease in the United Arab Emirates

Prevalence of rotavirus, norovirus and enterovirus in diarrheal diseases in Himachal Pradesh, India

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