Rotavirus vaccination in Europe: drivers and barriers

Parez, N.; Giaquinto, Carlo; Roure, C.; Martinón-Torres, Federico; Spoulou, Vana; Damme, Pierre Van; Vesikari, Timo

doi:10.1016/s1473-3099(14)70035-0

Cited by 73 publications

(68 citation statements)

References 67 publications

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“…Similar barriers have been identified in many European countries. 38 The ongoing crisis might have further negatively affected the uptake. Likewise, perceived need for vaccination against influenza seems to be low.…”

Section: Discussionmentioning

confidence: 99%

A cross-sectional vaccination coverage study in preschool children attending nurseries-kindergartens: Implications on economic crisis effect

Georgakopoulou

Menegas

Katsioulis

et al. 2017

Human Vaccines & Immunotherapeutics

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Vaccination coverage studies are important in determining a population's vaccination status and strategically adjusting national immunization programs. This study assessed full and timely vaccination coverage of preschool children aged 2-3 y attending nurseries-kindergartens (N-K) nationwide at the socioeconomic crisis onset. Geographically stratified cluster sampling was implemented considering prefectures as strata and N-K as clusters. The N-K were selected by simple random sampling from the sampling frame while their number was proportional to the stratum size. In total, 185 N-K (response rate 93.9%) and 2539 children (response rate 81.5%) participated. Coverage with traditional vaccines for diphtheria-tetanus-pertussis, polio and measles-mumps-rubella was very high (>95%), followed by Haemophilus influenzae type b and varicella vaccines. Despite very high final coverage, delayed vaccination was observed for hepatitis B (48.3% completed by 12 months). Significant delay was observed for the booster dose of pneumococcal conjugate vaccines (PCV) and meningococcal C conjugate vaccines (MCC). Of the total population studied, 82.3% received 3 PCV doses by 12 months, while 62.3% received the fourth dose by 24 months and 76.2% by 30 months. However, 89.6% received at least one MCC dose over 12 months. Timely vaccinated for hepatitis A with 2 doses by 24 months were 6.1%. Coverage was significantly low for Rotavirus (<20%) and influenza (23.1% one dose). High vaccination coverage is maintained for most vaccines at the beginning of the crisis in Greece. Coverage and timeliness show an increasing trend compared to previous studies. Sustained efforts are needed to support the preventive medicine system as socioeconomic instability continues.

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Section: Discussionmentioning

confidence: 99%

A cross-sectional vaccination coverage study in preschool children attending nurseries-kindergartens: Implications on economic crisis effect

Georgakopoulou

Menegas

Katsioulis

et al. 2017

Human Vaccines & Immunotherapeutics

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“…16 Rotavirus vaccination in countries with established vaccination programmes has consistently and significantly reduced the incidence of rotavirus gastroenteritis (RVGE) and associated hospitalizations, emergency department visits and outpatient/physician office visits in the United States (US), Europe and Australia. [17][18][19][20] Belgium introduced rotavirus vaccination in November 2006, with an uptake of 85% in the first year 21 and 89% in the second year. 22 This high vaccine uptake is maintained throughout subsequent years where parents are asked for a co-payment of the vaccine of 11.6€ per dose.…”

Section: Introductionmentioning

confidence: 99%

Improvement in hospital Quality of Care (QoC) after the introduction of rotavirus vaccination: An evaluation study in Belgium

Standaert

Alwan²,

Strens

et al. 2015

Human Vaccines & Immunotherapeutics

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During each winter period hospital emergency rooms and pediatric wards are often overwhelmed by high patient influx with infectious diseases leading to chaotic conditions with poor quality of care (QoC) delivery as a consequence. The conditions could be improved if we were able to better control the influx by introducing for instance better prevention strategies against some of the most frequent infectious diseases. New prevention strategies using vaccination against rotavirus infection were introduced in Belgium in November 2006. We developed a measure of hospital QoC suitable for assessing the impact of pediatric rotavirus vaccination. The study is retrospective collecting routine data on bed and staff management in one pediatric hospital in Belgium. The data were divided in pre-and post-vaccination periods during rotavirus-epidemic and non-epidemic periods. The scores were constructed using Explanatory Factor Analysis (EFA). All patients enrolled were admitted to the pediatric ward over the period from 1 January 2004 to 31 December 2009. The results of the epidemic period indicated that bed-day occupancy, bed-day turnover and unplanned readmissions for acute gastroenteritis were lower in the post-vaccination compared with the pre-vaccination periods. The QoC scores were therefore significantly lower (indicating improved QoC) after the introduction of rotavirus vaccination, compared with pre-vaccination. The data suggests that the reduction in the winter peak of rotavirus-related hospitalizations after the introduction of the vaccine reduces pressure on hospital resources and improves the quality of hospital care. The findings should be further tested in similar settings.

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“…This result was also in agreement with the fi ndings in the literature (10) (25) . An important reduction in admissions caused by gastroenteritis in children occurred in Europe, even in countries with low immunization coverage, for instance (30) .…”

Section: Methods Of Analysismentioning

confidence: 99%

The effectiveness of a rotavirus vaccine in preventing hospitalizations and deaths presumably due to acute infectious diarrhea in Brazilian children: a quasi-experimental study

Teles

Moscovici

Monteiro

et al. 2015

Rev. Soc. Bras. Med. Trop.

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Rotavirus vaccination in Europe: drivers and barriers

Cited by 73 publications

References 67 publications

A cross-sectional vaccination coverage study in preschool children attending nurseries-kindergartens: Implications on economic crisis effect

A cross-sectional vaccination coverage study in preschool children attending nurseries-kindergartens: Implications on economic crisis effect

Improvement in hospital Quality of Care (QoC) after the introduction of rotavirus vaccination: An evaluation study in Belgium

The effectiveness of a rotavirus vaccine in preventing hospitalizations and deaths presumably due to acute infectious diarrhea in Brazilian children: a quasi-experimental study

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