“…It has been estimated in less than 7%, the rate of spontaneous ruptures of the spleen appearing in histologically normal visceras (2). Spontaneous rupture of a pathologic spleen is much more frequent and may occur in all the disorders that induce splenomegaly: hematological (policitemia vera, hemolytic anemia, coagulation disorders, hemofilia, Waldenström macroglobulinemia), infectious (infectious mononucleosis, cytomegalovirus, paludism, bacterian endocarditis, typhoid fever, Q fever, splenic tuberculosis, brucellosis, acute viral hepatitis, rubella, amebiasis), tumoral (leukemia, lymphoma, angiosarcoma, hamartomas), miscellaneous: Sarcoidosis, acute pancreatitis, Gaucher disease, Ehrles-Danlos disease, NiemannPick disease, portal hypertension, pregnancy, postendoscopia, dialysis, spleen alterations (cysts, hemangiomas, infarction, abscess, splenic artery aneurysms, cavernous hemangioma) (1).…”