cal edema, warmth, or erythema at the procedural site (4). Risk assessments guide the appropriate use of prophylaxis based on procedural type, location, duration, initial condition, and patient health status (3). High-risk cardiac patients and individuals with prosthetic joints should receive prophylactic antibiotics for procedures that involve infected skin or breaching of the oral mucosa (5). Recent guidelines reported that the risk of infective endocarditis from bacterial exposure during daily activities is greater than the risk associated with specific procedures. The greatest change in prophylaxis guidelines redefined the high-risk population as patients with a history of infective endocarditis, prosthetic valve, cardiac transplant with persistent valvulopathy, prosthetic device repaired in the last 6 months, and congenital heart defect. These modifications eliminate 90% of patients who would receive prophylaxis based on the previous guidelines (3). Antibiotics may also be warranted for surgeries of the lower extremities or groin, wedge excisions of the lip or ear, nasal skin flaps, skin grafts, and severe inflammatory skin disease (6, 7). Numerous studies have demonstrated that antibiotic prophylaxis does not reduce the risk of SSI for uncomplicated dermatologic procedures (8-10). Due to the low risk of infection in dermatologic procedures and increasing rate of antimicrobial resistance, prophylactic antibiotics should be reserved for patient-specific circumstances and for procedures with > 5% risk of SSI.