Routine adherence monitoring after renal transplantation

Knight, Simon R.

doi:10.1111/tri.13422

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…Noncompliance also leads to waste, as it reduces the potential benefits of therapy, and to the extra cost of treating avoidable consequent morbidity [7]. Compliance to treatment is a crucial health issue for transplantation patients in clinical practice [8]. However, the rate of noncompliance to treatment after transplantation tends to increase with time [6,9].…”

Section: Introductionmentioning

confidence: 99%

A Cross-Sectional Analysis of Health Literacy and Compliance to Treatment in Organ Transplant Recipients

Bae

Lee

Son

et al. 2023

JCM

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This study was conducted to determine the correlations between health literacy, transplant effects, and compliance to treatment in organ transplant recipients and to identify the factors influencing compliance to treatment. The participants (n = 130; males = 66.9%; mean age = 56.4 years) were organ transplant recipients visiting an organ transplantation center in Seoul, South Korea. The regression model explained 32% of the variance in participants’ compliance to treatment. Among the health literacy variables, “Scale 3: Actively managing my health” (β = 0.38, p = 0.001) and “Scale 4: Social support for health” (β = 0.25, p = 0.019) had a significant effect on compliance to treatment. In this study, health literacy was identified as a key factor influencing compliance to treatment. Therefore, patients’ health literacy should be assessed prior to transplantation to identify potential high-risk patients for treatment nonadherence. In addition, after transplantation surgery, patient-tailored interventions should be developed and provided for self-management that reflects the patient’s health literacy level to ultimately enhance patient outcomes.

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Section: Introductionmentioning

confidence: 99%

A Cross-Sectional Analysis of Health Literacy and Compliance to Treatment in Organ Transplant Recipients

Bae

Lee

Son

et al. 2023

JCM

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“…Successful kidney transplantation requires strict adherence to chronic immunosuppressive regimens (1). Failure to take immunosuppressants as prescribed has been identified as a risk factor for adverse clinical outcomes among kidney transplant recipients (KTRs), including graft loss and reduced patient survival (2,3).…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, persistent medication nonadherence can lead to increased individual medical costs (4). Despite the obvious negative impact, medication nonadherence in KTRs remains substantial, with a broadly consistent prevalence of 20% or higher (1,5).…”

Section: Introductionmentioning

confidence: 99%

Illness Perceptions and Medication Nonadherence to Immunosuppressants After Successful Kidney Transplantation: A Cross-Sectional Study

Wang¹,

Veltkamp

Boog

et al. 2022

Transpl Int

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Background: Medication nonadherence to immunosuppressants is a well-known risk factor for suboptimal health outcomes in kidney transplant recipients (KTRs). This study examined the relationship between illness perceptions and medication nonadherence in prevalent Dutch KTRs and whether this relationship depended on post-transplant time.Methods: Eligible KTRs transplanted in Leiden University Medical Center were invited for this cross-sectional study. The illness perceptions and medication nonadherence were measured via validated questionnaires. Associations between illness perceptions and medication nonadherence were investigated using multivariable logistic regression models.Results: For the study, 627 participating KTRs were analyzed. 203 (32.4%) KTRs were considered nonadherent to their immunosuppressants with “taking medication more than 2 h from the prescribed dosing time” as the most prevalent nonadherent behaviour (n = 171; 27.3%). Three illness perceptions were significantly associated with medication nonadherence: illness identity (adjusted odds ratio [ORadj] = 1.07; 95% confidence interval [CI], 1.00–1.14), concern (ORadj = 1.07; 95%CI,1.00–1.14), and illness coherence (ORadj = 1.11; 95%CI,1.01–1.22). The relationships between illness perceptions and medication nonadherence did not differ depending on post-transplant time (p-values ranged from 0.48 to 0.96).Conclusion: Stronger negative illness perceptions are associated with medication nonadherence to immunosuppressants. Targeting negative illness perceptions by means of psychoeducational interventions could optimize medication adherence and consequently improve health outcomes in KTRs.

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Routine adherence monitoring after renal transplantation

Cited by 2 publications

References 8 publications

A Cross-Sectional Analysis of Health Literacy and Compliance to Treatment in Organ Transplant Recipients

A Cross-Sectional Analysis of Health Literacy and Compliance to Treatment in Organ Transplant Recipients

Illness Perceptions and Medication Nonadherence to Immunosuppressants After Successful Kidney Transplantation: A Cross-Sectional Study

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