Routine Measurements of Gluten Antibodies in Children of Short Stature

Screening children with severe short stature for celiac disease using tissue transglutaminase

“…The prevalence of CD was higher (35-59%) in the studies 11,[14][15][16][17][18] where either the endocrinal workup had been done and/or the sample was very small. In rest of the studies 10,13,[19][20][21][22][23][24] where the endocrinal causes had not been ruled out in the selected children and/or the sample size was relatively larger, the prevalence reported was lower (1.7-8.3%).…”

“…Firstly, the sample included in the present study was severely short stature (< -3SD) children whereas the earlier studies 10,13,19,[21][22][23][24] included children with moderate short stature (<-2 SD/< 3 rd percentile). At least two of the earlier investigation 20,25 have not defined the short stature criteria. Secondly, we are only reflecting the prevalence of tTG positivity and not the prevalence of CD.…”

Growth hormone impaired secretion and antipituitary antibodies in patients with coeliac disease and poor catch-up growth after a long gluten-free diet period: a causal association?

“…Coeliac disease (CD) is a permanent, genetically determined intolerance to gluten that results in entheropathy and frequent malabsorption in children that may impair final statural growth [4,7,8,27,31,32,43,46]. In fact, after starting a gluten-free diet (GFD), a significant increase in height and weight velocity has been evidenced [5,7,11,13,21,22,30], with weight reaching full catch-up growth in the first year of GFD and height reaching the expected centile after about 2 years [1,42,45].…”

Celiac Disease in an Adult Turkish Population with Type 1 Diabetes Mellitus

“…High-risk groups include first-degree relatives of patients with celiac disease, those with type 1 diabetes, and children with unexplained short stature (5)(6)(7)(8). Antigliadin antibodies (AGAs) were the first serological markers used widely in clinical practice for screening purposes.…”