Routine office hysteroscopy prior to ICSI and its impact on assisted reproduction program outcome: A randomized controlled trial

Shawki, Hossam Eldin; Elmorsy, Mahmoud; Eissa, Mostafa K.

doi:10.1016/j.mefs.2011.04.005

Cited by 25 publications

(42 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was in agreement with results found in previous studies conducted on women with unexplained infertility, before IUI and IVF cycles which revealed that the prevalence of unsuspected intrauterine abnormalities, diagnosed by hysteroscopy was in the range of 11%-45% [14,16,29,8,10,30]. The most common abnormality was intrauterine mild adhesions (15.5%), followed by small endometrial polyps (8.8%), submucous myoma (6.64%), short uterine septum (4.4%), endocervical lesions (3.34%), and chronic nonspecific endometritis (2.2%).…”

Section: Discussionsupporting

confidence: 92%

“…Currently, the gold standard technique for evaluation of the uterine cavity is HS, since it enables direct visualization of the uterine cavity and its relevant pathological disorders as well as the treatment of any detected abnormality in the same setting, unlike other indirect and purely diagnostic technique such as transvaginal sonography (TVS), hysterosalpingography (HSG), and saline infusion sonography (SIS) [6][7][8][9][10][11]. Nevertheless, the use of HS as a routine procedure in the infertility work-up is still under debate and there is no consensus on its efficacy and effectiveness in improving the prognosis of infertile couples [12].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of routine hysteroscopy (HS) prior to intrauterine insemination (IUI) on pregnancy rates (PR) among infertile couples at Al-Amal Hospital, Misurata, Libya

Elbareg¹,

Essadi²

2017

J Pregnancy Reprod

View full text Add to dashboard Cite

Objectives: To investigate the routine use of HS prior IUI in management of infertile women with main outcome measures studied was conception / PR. Materials and methods:Referred 180 patients, ages: 23-38 years with similar BMI and candidate for (COH) with IUI were included in a prospective controlled study for 2 years. Hormonal evaluation for all on day 3, divided into 2 groups; (A): underwent diagnostic HS to rule out intrauterine pathology (IUP), if found operated by HS before IUI, which has to be performed following cycle if normal or 2-3 cycles after operation. (B): Control (IUI without HS). Semen collected after 5 days of sexual abstinence, prepared by swim up technique, IUI performed with 0.5ml. Luteal support in all by oral dydrogestrone. Clinical PR: +ve pregnancy test and GS by (TVS) 4 weeks later & compared between the two gps. Any complications were recorded. Statistical analysis by using SPSS packages for Windows. P-value significant if (< 0.05).Results: out of 180 patients, 28/180 (15.5%) patients were lost in follow up: 18 from B group leaving 72/90 (80.0%), and 10 from A group, leaving 80/90 (88.8%). HS revealed no pathology in (58.8%), while (41.1%) were with abnormalities: (15.57%) mild adhesions, (8.86%) small endometrial polyps, (6.64%) small submucosal myomas, (4.46%) uterine septum, (3.34%) endocervical lesions, (2.21%) chronic non-specific endometritis, (abnormalities more in women aged ≥30 years and those with secondary infertility). No statistical difference in patient characteristics among groups. Pregnancy & pathology type relationship not significant (P > 0.623). Compared clinical PR in both gps after IUI was statistically significant (P< 0.05): 37/80 (46.25%) in HS group, and 18/80 (25%) in control group. All pregnancies in HS group occurred within first 2 IUI cycles. No significant reactions or surgical complications were recorded.Conclusions: HS before IUI is an effective and safe procedure in management of IUP, it improves significantly the chances of conception in infertile women before proceeding to more sophisticated and expensive treatment options.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Impact of routine hysteroscopy (HS) prior to intrauterine insemination (IUI) on pregnancy rates (PR) among infertile couples at Al-Amal Hospital, Misurata, Libya

Elbareg¹,

Essadi²

2017

J Pregnancy Reprod

View full text Add to dashboard Cite

show abstract

“…After the full text review, 111 studies were excluded and 9 studies were included, and 2 studies were included by hand search (March 10, 2020). Ultimately, a total of 11 studies were included [23,[32][33][34][35][36][37][38][39][40][41]. The basic characteristics of the included studies are shown in Table 1.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Six and 5 randomized and non-randomized controlled trials [32,33,35,37,39,40], [23,34,36,38,41], respectively, were selected that investigated the CPRs or LBRs in infertile women without intrauterine lesions after hysteroscopy. Of the 11 studies that were included, 4 (36.4%) were conducted in Turkey [32,36,38,41] and 2 (18.2%) in Iran [23,40], while others were conducted in Egypt [35], Greece [34], India [33], the Netherlands [39], and Europe (n=1 for all) [37]. All of the subjects included in the studies were diagnosed with infertility and planning to use ART (IVF/ICSI).…”

Section: Study Characteristicsmentioning

confidence: 99%

See 1 more Smart Citation

The Effect of Hysteroscopy on the Reproductive Outcomes of Infertile Women Without Intrauterine Pathologies: A Systematic Review and Meta-Analysis

Yang¹,

Lee²,

Chon³

2020

Preprint

View full text Add to dashboard Cite

(1) Background: The aim of this work was to systematically review existing studies on whether hysteroscopy improves the reproductive outcomes of women with infertility even in the absence of intrauterine pathologies when compared to women who did not receive a hysteroscopy. (2) Methods: We established the Participant-Intervention-Comparison-Outcome strategy and used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement to conduct a systematic review of 11 studies which were retrieved from 3 electronic databases: Ovid-Medline, Ovid-Embase, and the Cochrane Library. Two independent investigators extracted the data from the included studies and used the Cochrane risk-of-bias tool to assess their quality. (3) Results: The primary outcome measures were the clinical pregnancy rates (CPRs) and live birth rates (LBRs) in the in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles. Hysteroscopy in infertile women without intrauterine pathologies showed higher CPRs and LBRs than those in the same population who did not receive hysteroscopy in cases of recurrent implantation failure and IVF (odds ratio: 1.79 and 1.46, 95% confidence interval: 1.46-2.30 and 1.08-1.97 for CPR and LBR, respectively); however, the degree of significance was not as high for LBR. (4) Conclusions: Hysteroscopy before IVF/ICSI in infertile women without intrauterine pathologies may potentially be effective in improving the CPRs and LBRs in patients with RIF. Robust and high-quality randomized trials are warranted to confirm this finding.

show abstract

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities

Bosteels¹,

Kasius

Weyers

et al. 2013

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

Background Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are detectable in 10% to 15% of women seeking treatment for subfertility. Objectives To assess the effects of the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions suspected on ultrasound, hysterosalpingography, diagnostic hysteroscopy or any combination of these methods in women with otherwise unexplained subfertility or prior to intrauterine insemination (IUI), in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI).

show abstract

Routine office hysteroscopy prior to ICSI and its impact on assisted reproduction program outcome: A randomized controlled trial

Cited by 25 publications

References 20 publications

Impact of routine hysteroscopy (HS) prior to intrauterine insemination (IUI) on pregnancy rates (PR) among infertile couples at Al-Amal Hospital, Misurata, Libya

Impact of routine hysteroscopy (HS) prior to intrauterine insemination (IUI) on pregnancy rates (PR) among infertile couples at Al-Amal Hospital, Misurata, Libya

The Effect of Hysteroscopy on the Reproductive Outcomes of Infertile Women Without Intrauterine Pathologies: A Systematic Review and Meta-Analysis

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities

Contact Info

Product

Resources

About