Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries

Consensus Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS®) Society Recommendations Part 2—Emergency Laparotomy: Intra‐ and Postoperative Care

“…There is little specific evidence for wound protectors in EL, but a recent systematic review found some evidence of benefit for abdominal surgery in general, and no evidence of harm. A recent large cluster randomized trial in low- and middle-income countries, including a large proportion of emergency surgery patients and patients with intraoperative contamination, found that routine change of gloves and instruments before wound closure reduced surgical site infection by 13% [ 86 ]. Other key components to reduce SSI [ 87 ] include normothermia and control of blood glucose (both of which are discussed later in this document).…”

Comparative activities of ampicillin and teicoplanin against Enterococcus faecalis isolates

“…The prompt administration of efficient preoperative antibiotics and careful attention to surgical technique rank as the most crucial elements in the prevention of SSI, along with maintaining a clean operating room environment. A variety of topical and local antibiotic delivery methods as well as wound-protecting barrier devices have been employed during surgery to lower the incidence of SSI [36]. .The use of antimicrobial-coated sutures may minimize the risk of SSI, although the available and highquality data are scarce [37].…”

Metabolic syndrome and surgical complications: A systematic review and meta-analysis of 13 million individuals

“…Surgical optimisation interventions have shown promise for some of the diagnostic criteria of MetS such as treating obesity 93 and hypertension 94 prior to surgery, thus, there is the potential to adapt elements of existing interventions and guidelines for MetS patients to eliminate or reduce operative risks. It is also vital that the surgical team is attentive to practices that reduce SSI including weight-based dosing of prophylactic antibiotics 95 , redosing of prophylactic antibiotics in longer operations 96 , glucose optimisation 97 , glove changes 98 , and the use of alcoholic skin preparation prior to skin closure 99 . Postoperative follow-up and rehabilitation of these patients should also emphasise initiatives that reduce the risk of potential postoperative complications, such as SSIs 100 , 101 , venous thromboembolism events 102 , 103 , and cardiovascular complications 104 , 105 .…”