Routine use of LMWH prophylaxis is associated with a lower incidence of venous thromboembolic events following an ankle fracture

Juto, Hans; Hultin, Magnus; Möller, Michael; Morberg, Per

doi:10.1016/j.injury.2021.11.028

Injury

2022

DOI: 10.1016/j.injury.2021.11.028

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Routine use of LMWH prophylaxis is associated with a lower incidence of venous thromboembolic events following an ankle fracture

Hans Juto

Magnus Hultin

Michael Möller

et al.

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2024

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Cited by 1 publication

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Update on Venous Thromboembolism in Orthopaedic Trauma Surgery

Wills,

Gaski

2024

J Am Acad Orthop Surg

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Venous thromboembolism (VTE) is a notable contributor to the morbidity and mortality of patients with orthopaedic trauma. Several associations have published guidelines on VTE prophylaxis, with a strong predilection toward low-molecular-weight heparin for chemoprophylaxis. However, previous recommendations may be revisited because recent high-level evidence demonstrated aspirin to be noninferior to low-molecular-weight heparin in preventing serious complications of VTE. Direct oral anticoagulants are emerging as safe alternatives to injectable medication and may offer improved patient compliance. There is no consensus on postinjury duration of chemoprophylaxis as an outpatient. Mechanical prophylaxis remains an important adjunctive VTE preventive measure for inpatients with pelvis and extremity fractures. Proteomics and novel laboratory measurements may be able to predict high-risk patients and detect early thrombus formation. Despite high-quality prospective research over the past decade, we still have much to learn about patient- and injury-specific risk factors.

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Update on Venous Thromboembolism in Orthopaedic Trauma Surgery

Wills,

Gaski

2024

J Am Acad Orthop Surg

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show abstract

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Routine use of LMWH prophylaxis is associated with a lower incidence of venous thromboembolic events following an ankle fracture

Cited by 1 publication

References 23 publications

Update on Venous Thromboembolism in Orthopaedic Trauma Surgery

Update on Venous Thromboembolism in Orthopaedic Trauma Surgery

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