Routine versus selective upper gastrointestinal contrast series after omental patch repair for gastric or duodenal perforation

Poris, Stephenie; Fontaine, Andrew; Glener, Julie; Kubovec, Stacey; Veldhuis, Paula P.; Du, Yi; Pepe, Julie; Eubanks, Steve

doi:10.1007/s00464-017-5695-6

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…Also, it is reported ADSCs derived from subcutaneous adipose tissue can be regenerated and used by dermatology and in plastic surgery 17,18 . However, abdominal surgeons generally use omentum (visceral adipose tissue) for the repair of gastrointestinal perforations 19,20 . The authors have also experienced that these perforative points were completely replaced with regenerated tissues by an omental patch, thus digestive surgeons often have the impression that omentum has superior self-renewal ability.…”

Section: Discussionmentioning

confidence: 99%

The Differences in the Characteristics of Insulin-producing Cells Using Human Adipose-tissue Derived Mesenchymal Stem Cells from Subcutaneous and Visceral Tissues

Wada

Ikemoto

Morine

et al. 2019

Sci Rep

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The aim of this study was to investigate the characteristics of insulin producing cells (IPCs) differentiated from adipose-tissue derived stem cells (ADSCs) isolated from human subcutaneous and visceral adipose tissues and identify ADSCs suitable for differentiation into efficient and functional IPCs. Subcutaneous and visceral adipose tissues collected from four (4) patients who underwent digestive surgeries at The Tokushima University (000035546) were included in this study. The insulin secretion of the generated IPCs was investigated using surface markers by: fluorescence activated cell sorting (FACS) analysis; cytokine release; proliferation ability of ADSCs; in vitro (glucose-stimulated insulin secretion: (GSIS) test/in vivo (transplantation into streptozotocin-induced diabetic nude mice). The less fat-related inflammatory cytokines secretions were observed (P < 0.05), and the proliferation ability was higher in the subcutaneous ADSCs (P < 0.05). Insulin expression and GISI were higher in the subcutaneous IPCs (P < 0.01 and P < 0.05, respectively). The hyperglycaemic state of all mice that received IPCs from subcutaneous fat tissue converted into normo-glycaemia in thirty (30) days post-transplantation (4/4,100%). Transplanted IPCs were stained using anti-insulin and anti-human leukocyte antigen antibodies. The IPCs generated from the ADSCs freshly isolated from the human fat tissue had sufficient insulin secreting ability in vitro and in vivo.

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Section: Discussionmentioning

confidence: 99%

The Differences in the Characteristics of Insulin-producing Cells Using Human Adipose-tissue Derived Mesenchymal Stem Cells from Subcutaneous and Visceral Tissues

Wada

Ikemoto

Morine

et al. 2019

Sci Rep

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“…The median hospital length of stay for acute colonic perforation patients who received rapid source control laparotomy was 20 days (21). The length of stay for patient who received omental patch repair for gastric or duodenal perforation was 15.5 days (22). In our study, most patients were hospitalized within 20 days, although many patients were hospitalized for more than a month.…”

Section: Discussionmentioning

confidence: 56%

Effects of surgical treatment on 24465 patients with intestinal perforation complicated with septic shock in tertiary hospitals in China from 2017 to 2020: a systematic review

Wang

et al. 2021

Preprint

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Background Intestinal perforation often leads to abdominal infection and is one of the main causes of septic shock. Prompt surgical treatment is an important treatment for this disease. We designed this study to investigate the effects of surgical treatment on patients with intestinal perforation complicated with septic shock in China. Methods Tertiary hospitals were enrolled from the China National Critical Care Quality Control Center (China-NCCQC). The data were collected between January 1, 2017 and December 31, 2020. Intestinal perforation includes duodenal perforation, jejunal perforation, ileal perforation, colonic perforation, and rectal perforation. Sepsis 3.0 criteria were used for the diagnosis of septic shock. According to the above criteria, 26747 patients from 247915897 patients were selected. After excluding the missing data of gender, age and discharge mode, 24465 patients were remained. Results Patients with intestinal perforation complicated with septic shock in tertiary hospitals in China are more male and older patients. A significant proportion of patients were hospitalized for more than one month. The hospitalization cost per capita of these patients far exceeds the overall hospitalization cost per capita. In the operative group, the hospitalization days were longer. The operative group spent more. However, the incidence of complications was lower in the operative group. Patients with coronary heart disease (CHD) tended to be treated nonoperatively, and patients with systemic lupus erythematosus (SLE) tended to be treated surgically. 20% of the patients discharged against medical advice, 12% of the patients died. The operative group had a higher rate discharging with medical advice and a lower mortality rate. Conclusions For intestinal perforation complicated with septic shock in tertiary hospitals in China, patients who had surgery stayed longer and cost more. However, the incidence of complications was lower in the patients who had surgery. At the same time, the rate of discharging with medical advice was higher and the mortality rate was lower in the patients who had surgery.

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Minimally Invasive Treatment of Ulcer Disease: Laparoscopic Graham Patch, Laparoscopic Vagotomy and Antrectomy

Adkisson,

Weithorn

2024

Illustrative Handbook of General Surgery

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Routine versus selective upper gastrointestinal contrast series after omental patch repair for gastric or duodenal perforation

Cited by 4 publications

References 12 publications

The Differences in the Characteristics of Insulin-producing Cells Using Human Adipose-tissue Derived Mesenchymal Stem Cells from Subcutaneous and Visceral Tissues

The Differences in the Characteristics of Insulin-producing Cells Using Human Adipose-tissue Derived Mesenchymal Stem Cells from Subcutaneous and Visceral Tissues

Effects of surgical treatment on 24465 patients with intestinal perforation complicated with septic shock in tertiary hospitals in China from 2017 to 2020: a systematic review

Minimally Invasive Treatment of Ulcer Disease: Laparoscopic Graham Patch, Laparoscopic Vagotomy and Antrectomy

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