In the last 20 years, Emergency Management has received increasing attention from the scientific community. Meanwhile, the study of relief distribution networks has become one of the most popular topics within the Emergency Management field. In fact, the number and variety of contributions devoted to the design or the management of relief distribution networks has exploded in the recent years, motivating the need for a structured and systematic analysis of the works on this specific topic. To this end, this paper presents a systematic review of contributions on relief distribution networks in response to disasters. Through a systematic and scientific methodology, it gathers and consolidates the published research works in a transparent and objective way. It pursues three goals. First, to conduct an up-to-date survey of the research in relief distribution networks focusing on the logistics aspects of the problem, which despite the number of previous reviews has been overlooked in the past. Second, to highlight the trends and the most promising challenges in the modeling and resolution approaches and, finally, to identify future research perspectives that need to be explored.