Rowell Syndrome in a Middle-Aged Woman: A Case Report

Abstract

Rowell syndrome (RS) is characterized by the presentation of lupus erythematosus (LE) with erythema multiforme (EM)-like lesions. It is thought to display a characteristic serologic pattern consisting of a "speckled-type" antinuclear antibody (ANA), positive anti-Ro/SSA or anti-La/SSB, or positive rheumatoid factor (RF). We report the case of a patient with subacute cutaneous lupus erythematosus (SCLE) who presented with EM-like lesions responsive to oral corticosteroids.

A case of Rowell syndrome after a herpes simplex infection and prolonged sun exposure

“…Rowell Syndrome 1 is a rare entity combining EEM and lupus erythematosus (LE). [2][3][4][5][6][7][8] Zeitouni et al redefined Rowell Syndrome's diagnostic criteria. 2 Major criteria include: (1) LE (systemic, discoid or subacute cutaneous), (2) EEM-like skin lesions and (3) speckled pattern of ANA antibodies.…”

“…Rowell Syndrome 1 is a rare entity combining EEM and lupus erythematosus (LE). 2 , 3 , 4 , 5 , 6 , 7 , 8 Zeitouni et al. redefined Rowell Syndrome's diagnostic criteria.…”

“…The diagnosis is achieved when all major criteria and at least one minor criterion are present. 2 , 3 , 4 , 5 , 6 , 7 , 8 Prognosis and treatment regimens are those of EEM and LE, 8 with reported good response to oral cortisone, azathioprine, cyclosporine, dapsone, antimalarials 8 and methotrexate. 9 …”